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MGLUR1 + MGLUR5 Antibody, Biotin Conjugated

MGLUR1 + MGLUR5 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, MGLUR1 + MGLUR5 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMGLUR1 + MGLUR5
SpecificityThis is a highly specific antibody against MGLUR1 + MGLUR5
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human MGLUR1 + MGLUR5
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission, For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores, Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase, In expression systems, Recently, The Group-I receptors include Metabotropic Glutamate Receptor 5 and Metabotropic Glutamate Receptor 1a, The Group-II receptors in include mGluR2 and mGluR3, These receptors are called metabotropic glutamate receptors, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins, Glutamate is the main excitatory neurotransmitter in the brain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms MGLUR5 GPRC1E mGlu5 PPP1R86
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMGLUR1 + MGLUR5 Conjugated
Short name Conjugated, MGLUR1 + MGLUR5 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, MGLUR1 and MGLUR5 (Antibody to)
Alternative techniqueantibodies
Identity 4597
Gene GRM5
Long gene name glutamate metabotropic receptor 5
Synonyms gene name glutamate receptor, metabotropic 5
Synonyms name protein phosphatase 1, regulatory subunit 86
Locus 11q14, 2-q14, 3
Discovery year 1993-10-22
GenBank acession D28538
Entrez gene record 2915
Pubmed identfication 7908515
RefSeq identity NM_000842
Classification Glutamate metabotropic receptors Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000134306

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