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MKP-2/DUSP4 Antibody, Biotin Conjugated

MKP-2/DUSP4 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, MKP-2/DUSP4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMKP-2/DUSP4
SpecificityThis is a highly specific antibody against MKP-2/DUSP4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human MKP-2
Gene ID number1846
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, ERK2 and JNK, In addition, SAPK/JNK, These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues, They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, This gene product inactivates ERK1, Two alternatively spliced transcript variants, and different modes of inducibility of their expression by extracellular stimuli, and is localized in the nucleus, different tissue distribution and subcellular localization, encoding distinct isoforms, have been observed for this gene, is expressed in a variety of tissues, multiple polyadenylation sites have been reported, p38), which is associated with cellular proliferation and differentiation, DUSP4 is a member of the dual specificity protein phosphatase subfamily
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms HVH2 MKP-2 TYP
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMKP-2/DUSP4 Conjugated
Short name Conjugated, MKP-2/DUSP4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, MKP-2/DUSP4 (Antibody to)
Alternative techniqueantibodies
Identity 3070
Gene DUSP4
Long gene name dual specificity phosphatase 4
Synonyms name VH1 homologous phosphatase 2 MAP kinase phosphatase 2
Locus 8p12
Discovery year 1994-12-14
GenBank acession U21108
Entrez gene record 1846
Pubmed identfication 7535768 9205128
RefSeq identity NM_001394
Classification MAP kinase phosphatases
Havana BLAST/BLAT OTTHUMG00000133395

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