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MMP14 Antibody

MMP14 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMMP14
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the MMP14 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis MMP14 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P50281
PurityAntigen affinity
Description It acts as a positive regulator of cell growth and migration via activation of MMP15, Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, The protein encoded by this gene is a member of the membrane-type MMP subfamily, This gene is mapped to 14q11, This gene may be involved in actin cytoskeleton reorganization by cleaving PTK7, also called MT-MMP 1, and tissue remodeling, as well as in disease processes, is an enzyme that in humans is encoded by the MMP14 gene, reproduction, such as arthritis and metastasis, such as embryonic development, 2, Matrix metalloproteinase-14
ImmunogenAn amino acid sequence from the C-terminus of human Matrix metalloproteinase-14 (TPRRLLYCQRSLLDKV) was used as the immunogen for this MMP14 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MMP14 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMMP14
Short nameMMP14 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMMP14 (Antibody to)
Alternative techniqueantibodies
Identity 7160
Gene MMP14
Long gene name matrix metallopeptidase 14
Synonyms gene name matrix metalloproteinase 14 (membrane-inserted) matrix metallopeptidase 14 (membrane-inserted)
Synonyms MT1-MMP
Synonyms name membrane type 1 metalloprotease
Locus 14q11, 2
Discovery year 1994-11-20
Entrez gene record 4323
Pubmed identfication 8015608
RefSeq identity NM_004995
Classification Matrix metallopeptidases
Havana BLAST/BLAT OTTHUMG00000028704

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