Filters

MMP24 Antibody

MMP24 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMMP24
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the MMP24 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis MMP24 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9Y5R2
PurityAntigen affinity
Description However, Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases, Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, The gene has previously been referred to as MMP25 but has been renamed MMP24, This gene may be a proteoglycanase involved in degradation of proteoglycans, This protein activates MMP2 by cleavage, also known as MT5MMP and previously as MMP25, and tissue remodeling, as well as in disease processes, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted, is an enzyme that in humans is encoded by the MMP24 gene, reproduction, such as arthritis and metastasis, such as dermatan sulfate and chondroitin sulfate proteoglycans, such as embryonic development, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, Matrix metalloproteinase-24
Immunogen mouse and rat), An amino acid sequence from the N-terminus of human Matrix metalloproteinase-24 (YHEIKSDRKEADIMIFFA) was used as the immunogen for this MMP24 antibody (100% homologous in human
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MMP24 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMMP24
Short nameMMP24 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMMP24 (Antibody to)
Alternative techniqueantibodies
Identity 7172
Gene MMP24
Long gene name matrix metallopeptidase 24
Synonyms gene name matrix metalloproteinase 24 (membrane-inserted) matrix metallopeptidase 24 (membrane-inserted)
Synonyms MT5-MMP
Synonyms name membrane-type 5 matrix metalloproteinase
Locus 20q11, 22
Discovery year 1999-08-06
GenBank acession AF131284
Entrez gene record 10893
Pubmed identfication 10363975
RefSeq identity NM_006690
Classification Matrix metallopeptidases
Havana BLAST/BLAT OTTHUMG00000032330

Subscribe to our Newsletter