Name : MMS19 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8250694715
| Long name | ALEXA FLUOR 647 Conjugated, MMS19 Polyclonal Antibody |
| Also known as | Anti-MMS19 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MMS19 |
| Specificity | This is a highly specific antibody against MMS19 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 930-975/1030 |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MMS 19 |
| Gene ID Number | 64210 |
| Swiss Prot | Q96T76 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | As part of the mitotic spindle-associated MMXD complex, FANCJ and RTEL1, In the CIA complex, Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription, via its role in iron-sulfur insertion into some component of the TFIIH-machinery, Key component of the cytosolic iron-sulfur protein assembly (CIA) complex |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | MET18 hMMS19 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MMS19 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | MMS19 |
| Short name | MMS19 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, MMS19 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13824 |
| Gene | MMS19 |
| Long gene name | MMS19 homolog, cytosolic iron-sulfur assembly component |
| Synonyms gene | MMS19L |
| Synonyms gene name | MMS19 nucleotide excision repair homolog (S, cerevisiae) |
| Synonyms name | MET18 homolog (S, cerevisiae) |
| Locus | 10q24, 1 |
| Discovery year | 2000-12-21 |
| GenBank acession | AF007151 |
| Entrez gene record | 64210 |
| Pubmed identfication | 11071939 22678362 22678361 |
| Classification | Nucleotide excision repair Cytosolic iron-sulfur assembly components |
| Havana BLAST/BLAT | OTTHUMG00000018857 |