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MOUSE Anti-MBP (aa82-91) Antibody

MOUSE Anti-MBP (aa82-91) Antibody size: 0.25 ml 486

Supplier MBS MONO
Price 486
Size 0.25 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asMBP
Other names 20 kDa microtubule-stabilizing protein, Myelin A1 protein, Myelin basic protein, N/A, N/A, Myelin basic protein
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameMBP
Gene name synonimsN/A
Other gene names MBP, MBP, N/A, N/A
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
Clone10
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Bovine
Specificity and cross-reactivity <, <, In consequence the antibody is not a suitable reagent for sensitive immunoassays of correct human 82-91 as was thought at the time the original paper on this antibody was published, N, N, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Since this work was done a sequence error has been described in the human MBP sequence in this region Although the clone was selected to have a high affinity for 82-91 it appears that this antibody reacts more strongly with the unnatural sequence, The 91-92 phe-phe bond is believed to be cleaved by demyelinating lesions by Cathepsin D to generate peptides ending in the phe 91 which should react with this monoclonal, The clone was selected using synthetic human MBP peptide 82-91 for screening, This epitope is located in the C terminal region of 82-91 and the corresponding epitope is not present (or exposed) in whole MBP, This particular antibody might cross react with speacies outside of the listed ones, for details, for details, rather than the correct human 82-91, see Groome, see Groome, /i>, /i>, MBP It appears to react with synthetic peptide 82-91 and human and bovine 45-91 but not with whole MBP molecules (Martensen numbering), P, P, et al<, et al<, i>, i>
Purification methodN/A
Form/AppearanceAscites (Ascites fluid - liquid)
ConcentrationN/A
Storage and shipping If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term
Tested applications: ELISA (EIA), Western Blot (WB), Immunohistology - Frozen (IHC)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetMBP (aa82-91)
Short nameMOUSE Anti-MBP (aa82-91) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMOUSE antibody to-MBP (aa82-91) (Antibody to)
Alternative techniqueantibodies
Identity 6925
Gene MBP
Long gene name myelin basic protein
Locus 18q23
Discovery year 1986-01-01
Entrez gene record 4155
Pubmed identfication 2425357
RefSeq identity NM_001025081
Havana BLAST/BLAT OTTHUMG00000132874

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