Name : MOUSE Anti-PIG CD117 Antibody
Supplier : MBS MONO
Price :431
SKU : GEN8339244644
| Also known as | CD117 |
| Other names | Mast/stem cell growth factor receptor Kit, N/A, Proto-oncogene c-Kit, SCFR, Tyrosine-protein kinase Kit, c-kit, mast/stem cell growth factor receptor Kit, proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, tyrosine-protein kinase Kit, mast/stem cell growth factor receptor Kit |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CD117 |
| Gene name synonims | N/A |
| Other gene names | KIT, MGF, SCFR, KIT |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 2B8/BM |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Pig |
| Specificity and cross-reactivity | Clone 2B8/BM has been shown as suitable for use on cytospins, Clone 2B8/BM recognises CD117 on a small subset of porcine bone marrow progenitor cells and therefore provides an alternative tool from the previously used c-kit ligand stem cell factor, Haematopoietic stem cells (HSC) of bone marrow have multilineage differentiation potential and an extensive capacity for self-renewal, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The majority of adult bone marrow haematopoietic progenitor cells are CD117+ and have been used successfully in xenograft transplantation models for long term survival of grafts, This particular antibody might cross react with speacies outside of the listed ones, a 155kDa type I transmembrane protein with protein tyrosine kinase activity, also known as c-kit, for the isolation and enrichment of porcine stem cells, which plays an important role in early haematopoiesis, without symptoms of graft-versus-host disease (GVHD), CD117 Clone 2B8/BM is specific for porcine CD117 |
| Purification method | N/A |
| Form/Appearance | Purified (Purified IgG - liquid) |
| Concentration | 0mg/ml, IgG concentration 1 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target | CD117 |
| Short name | MOUSE Anti-PIG CD117 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MOUSE antibody to-swine CD117 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6342 |
| Gene | KIT |
| Long gene name | KIT proto-oncogene receptor tyrosine kinase |
| Synonyms gene | PBT |
| Synonyms gene name | piebald trait v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| Synonyms | CD117 SCFR C-Kit |
| Locus | 4q12 |
| Discovery year | 1986-01-01 |
| GenBank acession | S67773 |
| Entrez gene record | 3815 |
| Pubmed identfication | 9027509 |
| RefSeq identity | NM_000222 |
| Classification | CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000128713 |
| Locus Specific Databases | LRG_307 |