| Also known as | Growth Hormone Receptor / GHR |
| Other names | GH receptor, GH-binding protein, GHBPAlternative name(s):Serum-binding protein, Growth hormone receptor, Somatotropin receptorGrowth hormone-binding protein, growth hormone binding protein, growth hormone receptor, growth hormone receptor, serum binding protein, somatotropin receptor, growth hormone receptor isoform 1 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | GHR |
| Gene name synonims | N/A |
| Other gene names | GH receptor, GH-binding protein, GHBP, GHBP, GHR, GHR |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | N/A |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Has been validated for detection of GHR in formalin-fixed/paraffin-embedded human tissues, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antibody has been shown to partially block binding of GH in rabbit and rat and has been used as a growth hormone agonist, This particular antibody might cross react with speacies outside of the listed ones, Recognizes rat growth hormone receptor |
| Purification method | Protein A Purified |
| Form/Appearance | 0, pH 7, 09% sodium azide, 2, PBS |
| Concentration | 1 miligram per 1 mililiter |
| Storage and shipping | Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications: | Flow Cytometry (FC/FACS), IHC - Frozen), Immunoprecipitation (IP), Immunohistochemistry (IHC - Paraffin |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Description | FSH comprise the , Human recombinant LHRG and GHRH are produced in E, The glands that secrete Luteinizing hormones LHRG and LH, The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine , coli or in yeast cells, Hormone releasing factors and releasing hormones are , endocrine signaling system, glands , in , intracrine signaling) or nearby cells (paracrine signaling), multicellular organisms, or , produced by , signaling molecules |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , There are less rat- than mouse clones however, Monoclonals of this antigen are available in different clones, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Rattus norvegicus, Mus musculus |
| Gene target | Monoclonal (IgG1) Growth Hormone Receptor / GHR |
| Short name | Mouse Monoclonal (IgG1) Growth Hormone Receptor / GHR Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Host | Rat |
| Isotype | IgG1 |
| Species | Mouses, Rats, Rat |
| Alternative name | Mouse monoclonal (IgG1) to Rat Growth Hormone Receptor / growth hormone receptor (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | GHBP, GHR and IDBG-18930 and ENSG00000112964 and 2690, GHR and IDBG-629685 and ENSBTAG00000001335 and 280805, Ghr and IDBG-127871 and ENSMUSG00000055737 and 14600, nuclei, proline-rich region binding, this GO :0000187 and activation of MAPK activity and biological process this GO :0000255 and allantoin metabolic process and biological process this GO :0004903 and growth hormone receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006101 and citrate metabolic process and biological process this GO :0006103 and 2-oxoglutarate metabolic process and biological process this GO :0006105 and succinate metabolic process and biological process this GO :0006107 and oxaloacetate metabolic process and biological process this GO :0006549 and isoleucine metabolic process and biological process this GO :0006573 and valine metabolic process and biological process this GO :0006600 and creatine metabolic process and biological process this GO :0006631 and fatty acid metabolic process and biological process this GO :0006897 and endocytosis and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009725 and response to hormone and biological process this GO :0009755 and hormone-mediated signaling pathway and biological process this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017046 and peptide hormone binding and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019530 and taurine metabolic process and biological process this GO :0019838 and growth factor binding and molecular function this GO :0019898 and extrinsic component of membrane and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0031623 and receptor internalization and biological process this GO :0032094 and response to food and biological process this GO :0032355 and response to estradiol and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0034097 and response to cytokine and biological process this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0040018 and positive regulation of multicellular organism growth and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0042523 and positive regulation of tyrosine phosphorylation of Stat5 protein and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042976 and activation of Janus kinase activity and biological process this GO :0042977 and activation of JAK2 kinase activity and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043278 and response to morphine and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0044236 and multicellular organismal metabolic process and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0046427 and positive regulation of JAK-STAT cascade and biological process this GO :0046449 and creatinine metabolic process and biological process this GO :0046898 and response to cycloheximide and biological process this GO :0048009 and insulin-like growth factor receptor signaling pathway and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0060351 and cartilage development involved in endochondral bone morphogenesis and biological process this GO :0060396 and growth hormone receptor signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0070064 and proline-rich region binding and molecular function this GO :0070195 and growth hormone receptor complex and cellular component this GO :0070555 and response to interleukin-1 and biological process this GO :1901215 and negative regulation of neuron death and biological process, this GO :0004903: growth hormone receptor activity, this GO :0004903: growth hormone receptor activity and also this GO :0005515: protein binding and also this GO :0017046: peptide hormone binding and also this GO :0019838: growth factor binding and also this GO :0019901: protein kinase binding and also this GO :0019903: protein phosphatase binding and also this GO :0042169: SH2 domain binding and also this GO :0042803: protein homodimerization activity and also this GO :0070064: proline-rich region binding, this GO :0005515: protein binding, this GO :0017046: peptide hormone binding, this GO :0019838: growth factor binding, this GO :0019901: protein kinase binding, this GO :0019903: protein phosphatase binding, this GO :0042169: SH2 domain binding, this GO :0042803: protein homodimerization activity, this GO :0070064: proline-rich region binding, growth hormone receptor |
| Identity | 4263 |
| Gene | GHR |
| Long gene name | growth hormone receptor |
| Synonyms | GHBP |
| Synonyms name | growth hormone binding protein |
| Locus | 5p13, 1-p12 |
| Discovery year | 1989-06-30 |
| Entrez gene record | 2690 |
| RefSeq identity | NM_000163 |
| Classification | Fibronectin type III domain containing |
| Havana BLAST/BLAT | OTTHUMG00000094791 |
| Locus Specific Databases | LOVD - Leiden Open Variation Database |
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