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MPG Antibody

MPG Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMPG
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the MPG antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis MPG antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P29372
PurityAntigen affinity
Description Following treatment with DNA-methylating agents, Hang et al, The completely characterized human gene was found to span 7 to 8 kb of genomic DNA and to be localized 75 kb upstream of the embryonic zeta-globin gene, The gene was expressed in all cell lines and tissues examined, To assess the contribution of MPG to the repair of several mutagenic lesions in vivo, but was found at particularly high levels in a colon adenocarcinoma cell line (HT29), demonstrating an in vivo phenotype for the MPG-null animals, increased persistence of 7-methylguanine (meG) was found in liver sections of MPG knockout mice in comparison with wildtype mice, mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines, (1997) biochemically analyzed cell-free extracts of tissues from mice with a targeted deletion of the gene, N-Methylpurine-DNA glycosylase is encoded by the MPG gene
ImmunogenAn amino acid sequence from the C-terminus of human MPG (NKSFDQRDLAQDEAVW) was used as the immunogen for this MPG antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MPG antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMPG
Short nameMPG Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMPG (Antibody to)
Alternative techniqueantibodies
Identity 7211
Gene MPG
Long gene name N-methylpurine DNA glycosylase
Synonyms MDG
Synonyms name alkyladenine DNA glycosylase
Locus 16p13, 3
Discovery year 1989-12-11
Entrez gene record 4350
Pubmed identfication 1874728
Classification DNA glycosylases
Havana BLAST/BLAT OTTHUMG00000047887

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