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MTCO1 Antibody

MTCO1 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMTCO1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the MTCO1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis MTCO1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P00395
PurityAntigen affinity
Description 2 hemes and 2 copper centers, Acin-Perez et al, And they hypothesized that deleterious mutations can arise and become predominant, Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation, II, In mitochondrial Complex IV, It is composed of 13 polypeptides, MTCO2, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, MTCO3) of respiratory Complex IV, Subunits I, The 2 hemes and CuB are bound to subunit I, The cytochrome c oxidase family of enzymes have 4 redox centers, VIIa, VIIb, VIIc, VIa, VIb, VIc, Va, Vb, and III(MTCO1, and VIII are nuclear encoded, and that the size of a cavity in the vicinity of val421 in MTCO1I of animal COX may affect the function of the enzyme, cultured cells can maintain several mtDNA haplotypes at stable frequencies, the 2 hemes are a and a3 and the 2 coppers are CuA and CuB, the respiratory chain has little spare COX capacity, (2003) identified a cell line containing single and double missense mutations in the cytochrome c oxidase(COX) subunit I gene of mouse mitochondrial DNA, Cytochrome c oxidase subunit I(CO1 or MTCO1) is 1 of 3 mitochondrial DNA(mtDNA) encoded subunits(MTCO1
ImmunogenAn amino acid sequence from the N-terminus of human MTCO1 (FADRWLFSTNHKD) was used as the immunogen for this MTCO1 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MTCO1 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMTCO1
Short nameMTCO1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMTCO1 (Antibody to)
Alternative techniqueantibodies
Identity 7419
Gene MT-CO1
Long gene name mitochondrially encoded cytochrome c oxidase I
Synonyms gene MTCO1
Synonyms gene name cytochrome c oxidase I
Synonyms COX1 COI
Locus mitochondria
Discovery year 1989-10-12
Entrez gene record 4512
Pubmed identfication 7219534
RefSeq identity YP_003024028
Classification Mitochondrial complex IV: cytochrome c oxidase subunits

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