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MUC1 Antibody, Biotin Conjugated

MUC1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, MUC1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMUC1
SpecificityThis is a highly specific antibody against MUC1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1215-1255/1255
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human MUC1
Gene ID number4582
Swiss ProtP15941
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binds, Can act both as an adhesion and an anti-adhesion protein, In activated T-cells, May provide a protective layer on epithelial cells against bacterial and enzyme attack, Modulates signaling in ERK, Promotes tumor progression, Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response, SRC and NF-kappa-B pathways, The beta subunit contains a C-terminal domain which is involved in cell signaling, influences directly or indirectly the Ras/MAPK pathway, the PE21 promoter element of TP53 and represses TP53 activity, through phosphorylations and protein-protein interactions, together with KLF4, The alpha subunit has cell adhesive properties
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms CD227 PEM ADMCKD ADMCKD1 MCKD MCD
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMUC1 Conjugated
Short name Conjugated, MUC1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, MUC1 (Antibody to)
Alternative techniqueantibodies
Identity 7508
Gene MUC1
Long gene name cell surface associated , mucin 1
Synonyms gene PUM MCKD1
Synonyms gene name mucin 1, transmembrane medullary cystic kidney disease 1 (autosomal dominant)
Locus 1q22
Discovery year 1986-01-01
GenBank acession J05581
Entrez gene record 4582
Pubmed identfication 1697589 23396133
RefSeq identity NM_002456
Classification Mucins CD molecules
Havana BLAST/BLAT OTTHUMG00000035681

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