| Alternative name1 | Munc18, Munc18-1, Munc18a, N-Sec1, Rbsec1, STXBP1, Syntaxin Binding Protein 1, UNC-18, UNC18, Unc 18-1, Unc-18 Homolog, Unc-18-1, Unc-18A), Unc18 Homolog, Unc18A, hUNC18, p67, phosphorylated (Ser515) (Mammalian Homolog of Unc-18, Anti-Munc-18 |
| Alternative name2 | Munc18, Munc18-1, Munc18a, N-Sec1, Rbsec1, STXBP1, Syntaxin Binding Protein 1, UNC-18, UNC18, Unc 18-1, Unc-18 Homolog, Unc-18-1, Unc-18A), Unc18 Homolog, Unc18A, hUNC18, p67, phosphorylated (Ser515) (Mammalian Homolog of Unc-18, Munc-18 |
| Alternative name3 | Munc18, Munc18-1, Munc18a, N-Sec1, Rbsec1, STXBP1, Syntaxin Binding Protein 1, UNC-18, UNC18, Unc 18-1, Unc-18 Homolog, Unc-18-1, Unc-18A), Unc18 Homolog, Unc18A, hUNC18, p67, phosphorylated (Ser515) (Mammalian Homolog of Unc-18, Munc-18 |
| Alternative name4 | Munc-18 |
| Alternative name5 | Munc18, Munc18-1, Munc18a, N-Sec1, Rbsec1, STXBP1, Syntaxin Binding Protein 1, UNC-18, UNC18, Unc 18-1, Unc-18 Homolog, Unc-18-1, Unc-18A), Unc18 Homolog, Unc18A, hUNC18, p67, phosphorylated (Ser515) (Mammalian Homolog of Unc-18, Anti -Munc-18 |
| Other names | N/A |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | N/A |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | N/A |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Canine, Chicken, Human, Mouse, Rat, Xenopus, Bovine |
| Specificity and cross-reactivity | Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide, It is anticipated that the antibody will react with bovine, Specific for the ~65k Munc-18 protein phosphorylated at Ser515, canine, chicken, human, mouse, non-human primates and Xenopus based on the fact that these species have 100% homology with the amino acid sequence used as antigen, The antibody has been directly tested for reactivity in Western blots with rat tissue |
| Purification method | Affinity Purified by immunoaffinity chromatography |
| Form/Appearance | 100 ug/ml BSA and 50% glycerol, 150 mM NaCl, 10 mM Hepes (pH7, 5) |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | Munc18, Munc18-1, Munc18a, N-Sec1, Rbsec1, STXBP1, Syntaxin Binding Protein 1, UNC-18, UNC18, Unc 18-1, Unc-18 Homolog, Unc-18-1, Unc-18A), Unc18 Homolog, Unc18A, hUNC18, p67, phosphorylated (Ser515) (Mammalian Homolog of Unc-18, Munc-18 |
| Short name | Munc18, Munc18-1, Munc18a, N-Sec1, Rbsec1, STXBP1, Syntaxin Binding Protein 1, UNC-18, UNC18, Unc 18-1, Unc-18 Homolog, Unc-18-1, Unc-18A) Antibody, Unc18 Homolog, Unc18A, hUNC18, p67, phosphorylated (Ser515) (Mammalian Homolog of Unc-18, Munc-18 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Munc18, Munc18-1, Munc18a, N-Sec1, Rbsec1, Syntaxin Binding Protein 1, UNC-18, UNC18, Unc 18-1, Unc-18 Homolog, Unc-18-1, Unc-18A) (Antibody to), Unc18 Homolog, Unc18A, hUNC18, p67, phosphorylated (Ser515) (Mammalian Homolog on Unc-18, syntaxin binding protein 1, Munc-18 |
| Alternative technique | antibodies |
| Alternative to gene target | GABAergic and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043234 and protein complex and cellular component this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045921 and positive regulation of exocytosis and biological process this GO :0045956 and positive regulation of calcium ion-dependent exocytosis and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0050796 and regulation of insulin secretion and biological process this GO :0050821 and protein stabilization and biological process this GO :0060292 and long term synaptic depression and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070527 and platelet aggregation and biological process, MUNC18-1 and NSEC1 and P67 and RBSEC1 and UNC18, Plasma membranes, STXBP1 and IDBG-638972 and ENSBTAG00000003525 and 282378, STXBP1 and IDBG-86143 and ENSG00000136854 and 6812, Stxbp1 and IDBG-161623 and ENSMUSG00000026797 and 20910, protein N-terminus binding, this GO :0000149 and SNARE binding and molecular function this GO :0002576 and platelet degranulation and biological process this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006112 and energy reserve metabolic process and biological process this GO :0006887 and exocytosis and biological process this GO :0006904 and vesicle docking involved in exocytosis and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007269 and neurotransmitter secretion and biological process this GO :0007274 and neuromuscular synaptic transmission and biological process this GO :0007412 and axon target recognition and biological process this GO :0010807 and regulation of synaptic vesicle priming and biological process this GO :0014047 and glutamate secretion and biological process this GO :0015031 and protein transport and biological process this GO :0016188 and synaptic vesicle maturation and biological process this GO :0016192 and vesicle-mediated transport and biological process this GO :0017075 and syntaxin-1 binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0019905 and syntaxin binding and molecular function this GO :0031091 and platelet alpha granule and cellular component this GO :0032229 and negative regulation of synaptic transmission, this GO :0000149: SNARE binding, this GO :0000149: SNARE binding and also this GO :0005515: protein binding and also this GO :0017075: syntaxin-1 binding and also this GO :0019901: protein kinase binding and also this GO :0019904: protein domain specific binding and also this GO :0019905: syntaxin binding and also this GO :0042802: identical protein binding and also this GO :0044822: poly(A) RNA binding and also this GO :0047485: protein N-terminus binding, this GO :0005515: protein binding, this GO :0017075: syntaxin-1 binding, this GO :0019901: protein kinase binding, this GO :0019904: protein domain specific binding, this GO :0019905: syntaxin binding, this GO :0042802: identical protein binding, this GO :0044822: poly(A) RNA binding, this GO :0047485: protein N-terminus binding, syntaxin binding protein 1 |
| Identity | 11444 |
| Gene | STXBP1 |
| Long gene name | syntaxin binding protein 1 |
| Synonyms | hUNC18 MUNC18-1 UNC18 rbSec1 |
| Synonyms name | syntaxin-binding protein 1 |
| Locus | 9q34, 11 |
| Discovery year | 1996-12-27 |
| GenBank acession | AF004563 |
| Entrez gene record | 6812 |
| Pubmed identfication | 9545644 |
| RefSeq identity | NM_003165 |
| Havana BLAST/BLAT | OTTHUMG00000020713 |
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