| Alternative name1 | CLR19, FCAS2, Monarch 1, Monarch-1, NLR Family Pyrin Domain Containing 12, NLRP12, NT (NACHT LRR and PYD Domains-containing Protein 12, PAN6, PYPAF7, PYRIN Containing APAF1-like Protein 7, RNO, RNO2), Regulated by Nitric Oxide, 3, Anti-NALP12 |
| Alternative name2 | CLR19, FCAS2, Monarch 1, Monarch-1, NLR Family Pyrin Domain Containing 12, NLRP12, NT (NACHT LRR and PYD Domains-containing Protein 12, PAN6, PYPAF7, PYRIN Containing APAF1-like Protein 7, RNO, RNO2), Regulated by Nitric Oxide, 3, NALP12 |
| Alternative name3 | CLR19, FCAS2, Monarch 1, Monarch-1, NLR Family Pyrin Domain Containing 12, NLRP12, NT (NACHT LRR and PYD Domains-containing Protein 12, PAN6, PYPAF7, PYRIN Containing APAF1-like Protein 7, RNO, RNO2), Regulated by Nitric Oxide, 3, NALP12 |
| Alternative name4 | NALP12 |
| Alternative name5 | CLR19, FCAS2, Monarch 1, Monarch-1, NLR Family Pyrin Domain Containing 12, NLRP12, NT (NACHT LRR and PYD Domains-containing Protein 12, PAN6, PYPAF7, PYRIN Containing APAF1-like Protein 7, RNO, RNO2), Regulated by Nitric Oxide, 3, Anti -NALP12 |
| Other names | LRR and PYD containing protein 12, LRR and PYD domains-containing protein 12, LRR and PYD domains-containing protein 12, LRR and PYD domains-containing protein 12 isoform 2, Monarch-1, NACHT, NACHT, NACHT, NACHT, NLR family, OTTHUMP00000067226, OTTHUMP00000067227, OTTHUMP00000067228, OTTHUMP00000067229, PYRIN-containing APAF1-like protein 7, PYRIN-containing APAF1-like protein 7, Regulated by nitric oxide, leucine rich repeat and PYD containing 12, leucine rich repeat and pyrin domain containing 12, monarch 1, monarch-1, nucleotide-binding oligomerization domain, pyrin domain containing 12, regulated by nitric oxide, NACHT |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | CLR19, FCAS2, NALP12, NALP12, NLRP12, PAN6, PYPAF7, PYPAF7, RNO, RNO, RNO2, 3, NLRP12 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | Recognizes human NALP12 |
| Purification method | Purified by ammonium sulfate precipitation |
| Form/Appearance | 0, 09% sodium azide, Supplied as a liquid in PBS |
| Concentration | N/A |
| Storage and shipping | Aliquot to avoid repeated freezing and thawing, Aliquots are stable for at least 12 months, For maximum recovery of product, For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Immunohistochemistry (IHC), ELISA (EL/EIA) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | CLR19, FCAS2, Monarch 1, Monarch-1, NLR Family Pyrin Domain 12, NLRP12, NT (NACHT LRR PYD Domains Protein 12, PAN6, PYPAF7, PYRIN APAF1-like Protein 7, RNO, RNO2), Regulated by Nitric Oxide, 3, NALP12 |
| Short name | CLR19, FCAS2, Monarch 1, Monarch-1, NLR Family Pyrin Domain 12, NLRP12, NT (NACHT LRR PYD Domains-containing Protein 12, PAN6, PYPAF7, PYRIN APAF1-like Protein 7, RNO, RNO2) Antibody, Regulated by Nitric Oxide, 3, NALP12 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CLR19, FCAS2, Monarch 1, Monarch-1, NLR family, NLR family Pyrin Domain Containing 12, NT (NACHT LRR and PYD Domains-containing Protein 12, PAN6, PYPAF7, PYRIN Containing apoptotic peptidase activating factor 1-like Protein 7, RNO, RNO2) (Antibody to), Regulated by Nitric Oxide, pyrin domain containing 12, 3, NALP12 |
| Alternative technique | antibodies |
| Alternative to gene target | ADP binding, APAF-1 and CED4, APAF1 and IDBG-52364 and ENSG00000120868 and 317, APAF1 and IDBG-636787 and ENSBTAG00000021661 and 537782, Apaf1 and IDBG-185032 and ENSMUSG00000019979 and 11783, Cytoplasm, NLR family, NLRP12 and IDBG-641617 and ENSBTAG00000038149 and 522018, NLRP12 and IDBG-67727 and ENSG00000142405 and 91662, Nlrp12 and IDBG-264083 and ENSMUSG00000078817 and 378425, cysteine-type endopeptidase activator activity involved in apoptotic process, nuclei, pyrin domain containing 12, this GO :0000166 and nucleotide binding and molecular function this GO :0001843 and neural tube closure and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006952 and defense response and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007399 and nervous system development and biological process this GO :0007420 and brain development and biological process this GO :0008635 and activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0030900 and forebrain development and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043293 and apoptosome and cellular component this GO :0043531 and ADP binding and molecular function this GO :0051402 and neuron apoptotic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072432 and response to G1 DNA damage checkpoint signaling and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1902510 and regulation of apoptotic DNA fragmentation and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, this GO :0000166: nucleotide binding, this GO :0000166: nucleotide binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0042802: identical protein binding and also this GO :0043531: ADP binding, this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008588 and release of cytoplasmic sequestered NF-kappaB and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0009968 and negative regulation of signal transduction and biological process this GO :0031953 and negative regulation of protein autophosphorylation and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0036336 and dendritic cell migration and biological process this GO :0043122 and regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045345 and positive regulation of MHC class I biosynthetic process and biological process this GO :0045381 and regulation of interleukin-18 biosynthetic process and biological process this GO :0045409 and negative regulation of interleukin-6 biosynthetic process and biological process this GO :0045751 and negative regulation of Toll signaling pathway and biological process this GO :0050710 and negative regulation of cytokine secretion and biological process this GO :0050711 and negative regulation of interleukin-1 secretion and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process this GO :1901223 and negative regulation of NIK/NF-kappaB signaling and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0005524: ATP binding, this GO :0005524: ATP binding, this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0042802: identical protein binding, this GO :0043531: ADP binding, apoptotic peptidase activating factor 1 |
| Identity | 22938 |
| Gene | NLRP12 |
| Long gene name | NLR family pyrin domain containing 12 |
| Synonyms gene | NALP12 |
| Synonyms gene name | NACHT, leucine rich repeat and PYD containing 12 |
| Synonyms | RNO2 PYPAF7 Monarch1 PAN6 CLR19, 3 |
| Synonyms name | leucine rich repeat and pyrin domain containing 12 , nucleotide-binding oligomerization domain |
| Locus | 19q13, 42 |
| Discovery year | 2003-10-28 |
| GenBank acession | AY095146 |
| Entrez gene record | 91662 |
| Pubmed identfication | 12563287 12019269 |
| RefSeq identity | NM_144687 |
| Classification | NLR family Pyrin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000060776 |
| Locus Specific Databases | LRG_181 |
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