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NCAM2 Antibody

NCAM2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNCAM2 Primary Polyclonal Antibody
Also known asNCAM2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNCAM2
SpecificityThis is a highly specific antibody against NCAM2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NCAM2
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen NCAM2 contains five immunoglobulin-like domains, NCAM2 is a considered a good candidate for involvement in certain Down syndrome phenotypes because a slight overexpression of NCAMs increases many-fold the homotypic adhesion properties of cells, NCAM2 is a member of the neural cell adhesion molecule (NCAM) family, NCAMs are closely related cell surface glycoproteins involved in cell to cell interactions during growth and are thought to play an important role in embryogenesis and development, Neither Stat1 nor Stat3 bind to this region, Stat5 regulates NCAM2 in vivo by binding to the NCAM2 intron in the NKL natural killer cell line, The gene is expressed most strongly in human adult and fetal brain, a transmembrane domain and a cytoplasmic domain, despite sharing a consensus binding sequence with Stat5, this binding is induced by cytokines that activate Stat5, two Fibronectin type III domains, NCAM2 is an 837 amino acid protein encoded by the human gene NCAM2
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names N CAM 21, N CAM2, N CAM21, N-CAM-2, NCAM 2, NCAM 21, NCAM-2, NCAM21, NCAM2_HUMAN, Ncam2, Neural cell adhesion molecule 2, OCAM GPI, R4B12, RB 8 neural cell adhesion molecule, RB8 neural cell adhesion molecule, RNCAM, N CAM 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNCAM2
Short nameNCAM2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameneural cellular adhesion molecule 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target NCAM2 and IDBG-1027 and ENSG00000154654 and 4685, NCAM2 and IDBG-630332 and ENSBTAG00000003301 and 535613, NCAM21, Ncam2 and IDBG-172510 and ENSMUSG00000022762 and 17968, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007158 and neuron cell-cell adhesion and biological process this GO :0007413 and axonal fasciculation and biological process this GO :0007608 and sensory perception of smell and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0030424 and axon and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, neural cell adhesion molecule 2
Identity 7657
Gene NCAM2
Long gene name neural cell adhesion molecule 2
Synonyms NCAM21 MGC51008
Locus 21q21, 1
Discovery year 1997-04-25
Entrez gene record 4685
Pubmed identfication 9226371
RefSeq identity NM_004540
Classification Fibronectin type III domain containing I-set domain containing
Havana BLAST/BLAT OTTHUMG00000078121

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