Name : NCAPH2 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN6639735801
| Category | Antibody |
| Concentration | 09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | NCAPH2 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:1000 |
| Notes | Titration of the NCAPH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This NCAPH2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q6IBW4 |
| Purity | Purified |
| Description | A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase, An alternative complex, CAP-G, CAP-G2, CAP-H, CAP-H2, CAP-H2 is also known as Non-SMC condensin II complex, SMC2 and SMC4, The condensin I complex consists of two SMC subunits, The precise individual functions of each non-SMC protein in activation remain to be determined, The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex, and CAP-D2, and CAP-D3, and three non-SMC subunits, contains alternate non-SMC subunits, subunit H2 (NCAPH2) or kleisin beta isoform 2, the condensin II complex, Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation |
| Immunogen | A portion of amino acids 198-227 from the human protein was used as the immunogen for this NCAPH2 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NCAPH2 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | NCAPH2 |
| Short name | NCAPH2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | NCAPH2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 25071 |
| Gene | NCAPH2 |
| Long gene name | non-SMC condensin II complex subunit H2 |
| Synonyms gene name | non-SMC condensin II complex, subunit H2 |
| Synonyms | 384D8-2 hCAP-H2 CAP-H2 |
| Synonyms name | kleisin beta CAP-H2 subunit of the condensin II complex |
| Locus | 22q13, 33 |
| Discovery year | 2006-09-04 |
| GenBank acession | BC001937 |
| Entrez gene record | 29781 |
| Pubmed identfication | 10493829 |
| RefSeq identity | NM_152299 |
| Havana BLAST/BLAT | OTTHUMG00000150205 |