Name : NCR3 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5035649171
| Long name | NCR3 Primary Polyclonal Antibody |
| Also known as | NCR3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | NCR3 |
| Specificity | This is a highly specific antibody against NCR3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 95-135/201 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NCR3 |
| Gene ID number | 259197 |
| Swiss Prot | O14931 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, and inducing NK cells to release TNFA and IFNG, both through killing those DCs that did not properly acquire a mature phenotype, which promotes DC maturation, Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Activating natural killer receptor p30, CD337, LY117, MALS, NCR3, NK-p30, NKp30, Natural cytotoxicity triggering receptor 3, Natural killer cell p30-related protein, 1C7 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | NCR3 |
| Short name | NCR3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | natural cytotoxicity triggering receptor 3 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | NCR3 and IDBG-634145 and ENSBTAG00000018343 and 513769, NCR3 and IDBG-78112 and ENSG00000204475 and 259197, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0008037 and cell recognition and biological process this GO :0045954 and positive regulation of natural killer cell mediated cytotoxicity and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, natural cytotoxicity triggering receptor 3 |
| Identity | 19077 |
| Gene | NCR3 |
| Long gene name | natural cytotoxicity triggering receptor 3 |
| Synonyms gene | LY117 |
| Synonyms gene name | lymphocyte antigen 117 |
| Synonyms | 1C7 NKp30 CD337 |
| Locus | 6p21, 33 |
| Discovery year | 2002-08-05 |
| GenBank acession | AB055881 |
| Entrez gene record | 259197 |
| Pubmed identfication | 8824804 11782277 |
| Classification | CD molecules V-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000031123 |