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NHE3(Ser552) Antibody

NHE3(Ser552) Antibody size: 0.1ml 281

Price 281
Size 0.1ml
Long nameNHE3(Ser552) Primary Polyclonal Antibody
Also known asNHE3(Ser552) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNHE3 Ser552
SpecificityThis is a highly specific antibody against NHE3 Ser552
Modification(s)Phosphorylation
Modification site(s)Ser552
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human NHE-3 around the phosphorylation site of Ser552 [RG(p-S)LA](human Ser555)
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells, NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption, NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly, NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions, While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics, where they regulate intracellular pH and cell volume, NHE-3 are integral membrane proteins that are expressed in most mammalian tissues
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MGC126718, MGC126720, NHE 3, NHE-3, NHE3, Na+/H+ exchanger 3, SL9A3_HUMAN, SLC9A 3, Slc9a3, Sodium / Hydrogen Exchanger 3 phospho S552, Sodium/hydrogen exchanger, Sodium/hydrogen exchanger 3, Solute carrier family 9 member 3, Solute carrier family 9 sodium/hydrogen exchanger, Solute carrier family 9 sodium/hydrogen exchanger, apical epithelial, isoform 3, member 3, p-NHE-3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNHE3(Ser552)
Short nameNHE3(Ser552) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNHE3(Ser552) (Antibody to)
Alternative techniqueantibodies
Identity 11073
Gene SLC9A3
Long gene name solute carrier family 9 member A3
Synonyms gene NHE3
Synonyms gene name cation proton antiporter 3), isoform 3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 , member 3 solute carrier family 9, solute carrier family 9 (sodium/hydrogen exchanger), subfamily A (NHE3
Locus 5p15, 33
Discovery year 1992-06-12
Entrez gene record 6550
Pubmed identfication 8096830
RefSeq identity NM_004174
Classification Solute carriers
Havana BLAST/BLAT OTTHUMG00000090315

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