Name : NHE3(Ser552) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN6697459680
| Long name | NHE3(Ser552) Primary Polyclonal Antibody |
| Also known as | NHE3(Ser552) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | NHE3 Ser552 |
| Specificity | This is a highly specific antibody against NHE3 Ser552 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser552 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human NHE-3 around the phosphorylation site of Ser552 [RG(p-S)LA](human Ser555) |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells, NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption, NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly, NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions, While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics, where they regulate intracellular pH and cell volume, NHE-3 are integral membrane proteins that are expressed in most mammalian tissues |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | MGC126718, MGC126720, NHE 3, NHE-3, NHE3, Na+/H+ exchanger 3, SL9A3_HUMAN, SLC9A 3, Slc9a3, Sodium / Hydrogen Exchanger 3 phospho S552, Sodium/hydrogen exchanger, Sodium/hydrogen exchanger 3, Solute carrier family 9 member 3, Solute carrier family 9 sodium/hydrogen exchanger, Solute carrier family 9 sodium/hydrogen exchanger, apical epithelial, isoform 3, member 3, p-NHE-3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | NHE3(Ser552) |
| Short name | NHE3(Ser552) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | NHE3(Ser552) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11073 |
| Gene | SLC9A3 |
| Long gene name | solute carrier family 9 member A3 |
| Synonyms gene | NHE3 |
| Synonyms gene name | cation proton antiporter 3), isoform 3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 , member 3 solute carrier family 9, solute carrier family 9 (sodium/hydrogen exchanger), subfamily A (NHE3 |
| Locus | 5p15, 33 |
| Discovery year | 1992-06-12 |
| Entrez gene record | 6550 |
| Pubmed identfication | 8096830 |
| RefSeq identity | NM_004174 |
| Classification | Solute carriers |
| Havana BLAST/BLAT | OTTHUMG00000090315 |