Filters

Nicalin/NCLN Antibody

Nicalin/NCLN Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNicalin/NCLN Primary Polyclonal Antibody
Also known asNicalin/NCLN PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNicalin/NCLN
SpecificityThis is a highly specific antibody against Nicalin/NCLN
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Nicalin
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Nicalin, Nodal signaling is an important factor for melanoma cell invasiveness and tumorigenicity and inhibition of this signal can promote melanoma cells reverting back toward a melanocyte phenotype, Nodals are TGF beta signaling factors that control various cell fate decisions during embryonic body planning stages in vertebrate development, The Nicalin/NOMO complex acts to regulate the nodal signaling factors during gastrulation, This regulation most often affects the development of the axial mesoderm, a nicastrin-like protein, is not associated with gamma-secretase but rather interacts with NOMO (Nodal modulator), Nicastrin is an integral part of the Alzheimers associated gamma-secretase complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NCLN_HUMAN, NET59, Nicalin, Nicalin homolog zebrafish, Nicastrin like protein, Nicastrin-like protein, NCLN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNicalin/NCLN
Short nameNicalin/NCLN Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNicalin/NCLN (Antibody to)
Alternative techniqueantibodies
Identity 26923
Gene NCLN
Long gene name nicalin
Synonyms gene name nicalin homolog (zebrafish)
Synonyms NICALIN NET59
Synonyms name nicastrin-like protein
Locus 19p13, 3
Discovery year 2004-11-26
GenBank acession BC025926
Entrez gene record 56926
Pubmed identfication 11230166
RefSeq identity NM_020170
Havana BLAST/BLAT OTTHUMG00000180687

Similar products

Subscribe to our Newsletter