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NIPA(Ser354) Antibody, Cy7 Conjugated

NIPA(Ser354) Antibody, Cy7 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, NIPA(Ser354) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNIPA Ser354
SpecificityThis is a highly specific antibody against NIPA Ser354
ModificationPhosphorylation
Modification siteSer354
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human NIPA around the phosphorylation site of Ser354
Gene ID number51530
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Assembly of this SCF complex is regulated by cell-cycle-dependent phosphorylation of NIPA, Inactivation of NIPA by RNAi results in nuclear accumulation of cyclin B1 in interphase, NIPA (nuclear interaction partner of ALK) is a human F-box-containing protein that defines an SCF-type E3 ligase (SCFNIPA) controlling mitotic entry, Nuclear cyclin B1 is a substrate of SCFNIPA, SCFNIPA-based ubiquitination may regulate S-phase completion and mitotic entry in the mammalian cell cycle, The SCF class of E3 ubiquitin ligases is involved in this process by targeting cell cycle regulatory proteins for degradation by the proteasome, Thus, activation of cyclin B1-Cdk1 kinase activity, and premature mitotic entry, which restricts substrate ubiquitination activity to interphase, with the F-box subunit of the SCF specifically recruiting a given substrate to the SCF core, The regulated oscillation of protein expression is an essential mechanism of cell cycle control
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms NIPA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetNIPA(Ser354) Conjugated
Short name Conjugated, NIPA(Ser354) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, NIPA(Ser354) (Antibody to)
Alternative techniqueantibodies
Identity 29913
Gene ZC3HC1
Long gene name zinc finger C3HC-type containing 1
Synonyms name nuclear interaction partner of ALK
Locus 7q32, 2
Discovery year 2004-11-19
GenBank acession AF151050
Entrez gene record 51530
Pubmed identfication 11042152
RefSeq identity NM_016478
Classification Zinc fingers
Havana BLAST/BLAT OTTHUMG00000157648

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