Name : NLRP12 (228CT4.1.3) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :328
SKU : GEN6123057848
| Long name | 1, 3) Monoclonal Antibody, NLRP12 (228CT4 |
| Also known as | 1, 3) Monoclonal Antibody, NLRP12 (228CT4 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | NLRP12 |
| Specificity | This is a highly specific antibody against NLRP12 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1, 228CT4, 3 |
| Source | This NLRP12 monoclonal antibody is generated from mouse immunized with NLRP12 recombinant protein |
| Gene ID number | 91662 |
| Swiss Prot | P59046 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:100~1600) |
| Cross reactivity | Mouse |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK |
| Purification method | 09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CLR19, FCAS2, LRR and PYD domains-containing protein 12, Monarch-1, NACHT, NALP12, NLRP12, PAN6, PYPAF7, PYRIN-containing APAF1-like protein 7, RNO2, Regulated by nitric oxide, 3, RNO |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 1, 3) Monoclonal, NLRP12 (228CT4 |
| Short name | 1, 3) Monoclonal Antibody, NLRP12 (228CT4 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | pyrin domain containing 12 (228CT4, 1, 3) monoclonal (Antibody to), NLR family |
| Alternative technique | antibodies |
| Alternative to gene target | Cytoplasm, NLRP12 and IDBG-641617 and ENSBTAG00000038149 and 522018, NLRP12 and IDBG-67727 and ENSG00000142405 and 91662, Nlrp12 and IDBG-264083 and ENSMUSG00000078817 and 378425, cysteine-type endopeptidase activator activity involved in apoptotic process, pyrin domain containing 12, this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008588 and release of cytoplasmic sequestered NF-kappaB and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0009968 and negative regulation of signal transduction and biological process this GO :0031953 and negative regulation of protein autophosphorylation and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0036336 and dendritic cell migration and biological process this GO :0043122 and regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045345 and positive regulation of MHC class I biosynthetic process and biological process this GO :0045381 and regulation of interleukin-18 biosynthetic process and biological process this GO :0045409 and negative regulation of interleukin-6 biosynthetic process and biological process this GO :0045751 and negative regulation of Toll signaling pathway and biological process this GO :0050710 and negative regulation of cytokine secretion and biological process this GO :0050711 and negative regulation of interleukin-1 secretion and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process this GO :1901223 and negative regulation of NIK/NF-kappaB signaling and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0005524: ATP binding, this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, NLR family |
| Identity | 22938 |
| Gene | NLRP12 |
| Long gene name | NLR family pyrin domain containing 12 |
| Synonyms gene | NALP12 |
| Synonyms gene name | NACHT, leucine rich repeat and PYD containing 12 |
| Synonyms | RNO2 PYPAF7 Monarch1 PAN6 CLR19, 3 |
| Synonyms name | leucine rich repeat and pyrin domain containing 12 , nucleotide-binding oligomerization domain |
| Locus | 19q13, 42 |
| Discovery year | 2003-10-28 |
| GenBank acession | AY095146 |
| Entrez gene record | 91662 |
| Pubmed identfication | 12563287 12019269 |
| RefSeq identity | NM_144687 |
| Classification | NLR family Pyrin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000060776 |
| Locus Specific Databases | LRG_181 |