Name : NOTCH4 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN1164169973
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | NOTCH4 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:2000 |
| Notes | Titration of the NOTCH4 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This NOTCH4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q99466 |
| Purity | Antigen affinity |
| Description | Affects the implementation of differentiation, Jagged2 and Delta1 to regulate cell-fate determination, May regulate branching morphogenesis in the developing vascular system (By similarity), Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus, proliferation and apoptotic programs, Functions as a receptor for membrane-bound ligands Jagged1 |
| Immunogen | This NOTCH4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1819-1851 amino acids from the C-terminal region of human NOTCH4 |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NOTCH4 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | NOTCH4 |
| Short name | NOTCH4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | NOTCH4 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 5567 |
| Gene | IGHV1OR15-5 |
| Long gene name | immunoglobulin heavy variable 1/OR15-5 (non-functional) |
| Synonyms gene name | immunoglobulin heavy variable 1/OR15-5 immunoglobulin heavy variable 1/OR15-5 pseudogene immunoglobulin heavy variable 1/OR15-5 (pseudogene) |
| Synonyms | IGHV1/OR15-5 |
| Locus | 15q11, 2 not on reference assembly |
| Discovery year | 2000-04-17 |
| GenBank acession | Z29633 |
| Entrez gene record | 100384884 |
| RefSeq identity | NG_016978 |
| Classification | Immunoglobulin heavy (IGH) orphons |