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NOTUM Antibody

NOTUM Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNOTUM Primary Polyclonal Antibody
Also known asNOTUM PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNOTUM
SpecificityThis is a highly specific antibody against NOTUM
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NOTUM
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen BRCA1 is directly involved in DNA repair, Encoding more than 1, Like p53, Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome, The gene that encodes Notum consists of approximately 9, Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death, Two key tumor suppressor genes are associated with chromosome 17, chromosome 17 comprises over 2, colon, namely, p53 and BRCA1, prostate gland and fallopian tubes, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of ovary, 200 genes, 3, 334 bases and maps to human chromosome 17q25, 5% of the human genome, Notum is a 496 amino acid secreted protein that belongs to the pectinacetylesterase family and may deacetylate GlcNAc residues on cell surface glycans
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NOTUM_HUMAN, Notum pectinacetylesterase homolog, notum pectinacetylesterase homolog Drosophila, NOTUM
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNOTUM
Short nameNOTUM Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNOTUM (Antibody to)
Alternative techniqueantibodies
Identity 27106
Gene NOTUM
Long gene name NOTUM, palmitoleoyl-protein carboxylesterase
Synonyms gene name notum pectinacetylesterase homolog (Drosophila)
Synonyms name [Wnt protein] O-palmitoleoyl-L-serine hydrolase
Locus 17q25, 3
Discovery year 2005-11-22
GenBank acession BC060882
Entrez gene record 147111
Pubmed identfication 25731175
RefSeq identity NM_178493
Havana BLAST/BLAT OTTHUMG00000154416

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