| Category | Antibody |
| Concentration | pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | NR1H2 |
| Host animal | Goat (Capra aegagrus hircus) |
| Clonality | Polyclonal (goat origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA (peptide), IHC, WB |
| Recommended dilutions | ELISA (peptide) LOD: 1:64000, Immunohistochemistry (FFPE): 1-2ug/ml, Western blot: 1-3ug/ml |
| Notes | Optimal dilution of the NR1H2 antibody should be determined by the researcher |
| Intented use | This NR1H2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID # | 7376 |
| Purity | Antigen affinity |
| Description | group H, member 2, Additional name(s) for this target protein: Nuclear receptor subfamily 1 |
| Immunogen | This sequence is specific to NR1H2/LXR beta and will not cross react with LXR alpha, Amino acids SSPTTSSLDTPLPGC were used as the immunogen for this NR1H2 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the NR1H2 antibody at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | NR1H2 |
| Short name | NR1H2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | family H, member 2 (Antibody to), nuclear receptor subfamily 1 |
| Alternative technique | antibodies |
| Alternative to gene target | ATPase binding, BT, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0010467 and gene expression and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010867 and positive regulation of triglyceride biosynthetic process and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0010887 and negative regulation of cholesterol storage and biological process this GO :0030522 and intracellular receptor signaling pathway and biological process this GO :0032270 and positive regulation of cellular protein metabolic process and biological process this GO :0032369 and negative regulation of lipid transport and biological process this GO :0032376 and positive regulation of cholesterol transport and biological process this GO :0034191 and apolipoprotein A-I receptor binding and molecular function this GO :0043401 and steroid hormone mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044255 and cellular lipid metabolic process and biological process this GO :0045723 and positive regulation of fatty acid biosynthetic process and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046965 and retinoid X receptor binding and molecular function this GO :0048384 and retinoic acid receptor signaling pathway and biological process this GO :0048550 and negative regulation of pinocytosis and biological process this GO :0051006 and positive regulation of lipoprotein lipase activity and biological process this GO :0051117 and ATPase binding and molecular function this GO :0060336 and negative regulation of interferon-gamma-mediated signaling pathway and biological process this GO :2000188 and regulation of cholesterol homeostasis and biological process, LXR-b and LXRB and NER and NER-I and RIP15 and UNR, NR1H2 and IDBG-64316 and ENSG00000131408 and 7376, Nr1h2 and IDBG-179265 and ENSMUSG00000060601 and 22260, group H, member 2, nuclei, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001133 and sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003707 and steroid hormone receptor activity and molecular function this GO :0004879 and ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001133: sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003707: steroid hormone receptor activity and also this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0034191: apolipoprotein A-I receptor binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0046965: retinoid X receptor binding and also this GO :0051117: ATPase binding, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001133: sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003707: steroid hormone receptor activity, this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0034191: apolipoprotein A-I receptor binding, this GO :0043565: sequence-specific DNA binding, this GO :0046965: retinoid X receptor binding, this GO :0051117: ATPase binding, 44371 and IDBG-641008 and ENSBTAG00000003264 and 509622, nuclear receptor subfamily 1 |
| Identity | 7965 |
| Gene | NR1H2 |
| Long gene name | nuclear receptor subfamily 1 group H member 2 |
| Synonyms gene | UNR |
| Synonyms gene name | group H, member 2 , ubiquitously-expressed nuclear receptor nuclear receptor subfamily 1 |
| Synonyms | NER NER-I RIP15 LXR-b |
| Synonyms name | liver X receptor-beta |
| Locus | 19q13, 3 |
| Discovery year | 1994-09-19 |
| GenBank acession | U14534 |
| Entrez gene record | 7376 |
| Pubmed identfication | 7782080 7971966 |
| Classification | Nuclear hormone receptors |
| Havana BLAST/BLAT | OTTHUMG00000183036 |
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