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NTN3/Netrin-3 Antibody, FITC Conjugated

NTN3/Netrin-3 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, NTN3/Netrin-3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNTN3/Netrin-3
SpecificityThis is a highly specific antibody against NTN3/Netrin-3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human NTN3/Netrin-3
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background During peripheral nerve development, In axonal cells, In humans, Neogenin serves as the primary guidance receptor for netrin-3, Neogenin serves as the primary guidance receptor for netrin-3, Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity, Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, Netrin-3 proteins are associated with the axon fibers projecting from motor neurons and from neurons within sympathetic and sensory ganglia, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins as the cells are repelled, and, by the netrin gradient, high netrin-3 expression has been detected in mesenchymal cells, like netrin-1, rather than attracted, sensory ganglia and muscles, suggesting that netrin-3 may be involved in pathfinding and fasciculation of axon projection, the gene encoding for the netrin-3 protein is localized to chromosome 16p13, they can either attract or repel commissural axons at a distance, 3, Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetNTN3/Netrin-3 Conjugated
Short name FITC Conjugated, NTN3/Netrin-3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, NTN3/Netrin-3 (Antibody to)
Alternative techniqueantibodies
Identity 8030
Gene NTN3
Long gene name netrin 3
Synonyms gene NTN2L
Synonyms gene name netrin 2 (chicken)-like netrin 2-like (chicken)
Synonyms name Netrin-3
Locus 16p13, 3
Discovery year 1997-02-05
GenBank acession U86759
Entrez gene record 4917
Pubmed identfication 9143507 10366627
RefSeq identity NM_006181
Classification Netrins
Havana BLAST/BLAT OTTHUMG00000128867

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