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ODF2/Cenexin1 Antibody, FITC Conjugated

ODF2/Cenexin1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, ODF2/Cenexin1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenODF2/Cenexin1
SpecificityThis is a highly specific antibody against ODF2/Cenexin1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human ODF2/Cenexin1
Gene ID number4957
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Cenexin1 acts as a general scaffold protein that is specifically localised to the distal/subdistal appendages of mother centrioles, Cenexin1 is required for proper localization of Plk1 to the centrosomes, Cenexin1 is required for proper mitotic progression, Cenexin1 recruits Plk1 via a C-terminal extension of cenexin1 that is not present in ODF2, ODF2 is a major component of sperm tail outer dense fibers (ODFs), ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail, The ODF2 (outer dense fiber 2) gene encodes both ODF2 and Cenexin1, They may help to maintain the passive elastic structures and elastic recoil of the sperm tail, This centrosomal localization of Plk1 is required for proper microtubule function, and may also modulate sperm motility, depletion of Cenexin1 ultimately leads to chromosome missegregation and apoptosis, that unlike ODF2 is present in several somatic cell types, which have very different functions, Cenexin1 is an isoform of ODF2
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms ODF84 CT134
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetODF2/Cenexin1 Conjugated
Short name FITC Conjugated, ODF2/Cenexin1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, ODF2/Cenexin1 (Antibody to)
Alternative techniqueantibodies
Identity 8114
Gene ODF2
Long gene name outer dense fiber of sperm tails 2
Synonyms gene name outer dense fibre of sperm tails 2
Synonyms name cancer/testis antigen 134 cenexin
Locus 9q34, 11
Discovery year 1998-07-03
GenBank acession AF012549
Entrez gene record 4957
Pubmed identfication 9045620 10072582
Havana BLAST/BLAT OTTHUMG00000020748

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