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OSBP Antibody

OSBP Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenOSBP
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the OSBP antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis OSBP antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P22059
PurityAntigen affinity
Description 20- and 25-hydroxy cholesterol, Cytosolic OSBP formed an approximately 440-kD oligomer with a member of the PTPPBS family of tyrosine phosphatases, Im et al, Moreira et al, Wang et al, a member of the OSBP-related protein (ORP) family, and 7-, and cholesterol, at 1, cholesterol, the serine/threonine phosphatase PP2A, (2001) refined the localization of the OSBP1 gene to chromosome 11q12, (2005) found that OSBP functions as a cholesterol-binding scaffolding protein coordinating the activity of 2 phosphatases to control the extracellular signal-regulated kinase (ERK) signaling pathway, (2005) reported the structure of the full-length yeast oxysterol-binding-protein Osh4, 1 by radiation hybrid analysis, 5- to 1, 9-angstrom resolution in complexes with ergosterol, Oxysterol-Binding Protein is a protein that in humans is encoded by the OSBP gene
Immunogen mouse and rat), An amino acid sequence from the middle region of human Oxysterol-Binding Protein (WQKSLQYERDQRIRL) was used as the immunogen for this OSBP antibody (100% homologous in human
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the OSBP antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetOSBP
Short nameOSBP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameOSBP (Antibody to)
Alternative techniqueantibodies
Identity 8503
Gene OSBP
Long gene name oxysterol binding protein
Synonyms OSBP1
Locus 11q12, 1
Discovery year 1990-01-03
GenBank acession AF185696
Entrez gene record 5007
Classification Pleckstrin homology domain containing Oxysterol binding proteins
Havana BLAST/BLAT OTTHUMG00000167422

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