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OSBP2 Antibody

OSBP2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameOSBP2 Primary Polyclonal Antibody
Also known asOSBP2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenOSBP2
SpecificityThis is a highly specific antibody against OSBP2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OSBP2
Gene ID number23762
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen HMG-CoA reductase and the low density lipoprotein receptor (LDLR), OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), OSBP localizes to the cytosol and is widely expressed, OSBPs are involved in lipid metabolism and signal transduction, The OSBP protein transports sterols from lysosomes to the nucleus, The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties, a suppressor of cholesterol synthesis gene transcription in cultured cells, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols, as well as vesicle transport, retina and fetal liver, where sterols downregulate the genes for HMG synthetase, which share a high overall similarity, while OSBP2 is mainly detected in testis, The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ORP4, OSBLP4, OSBP-related protein 4, OSBP2, OSBP2_HUMAN, OSBPL1, OSBPL4, Oxysterol Binding Protein 2, Oxysterol Binding Protein-like 1, oxysterol binding protein-related protein 4, ORP 4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetOSBP2
Short nameOSBP2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameOSBP2 (Antibody to)
Alternative techniqueantibodies
Identity 8504
Gene OSBP2
Long gene name oxysterol binding protein 2
Synonyms gene OSBPL1
Synonyms KIAA1664 ORP-4 ORP4
Locus 22q12, 2
Discovery year 1999-10-29
Entrez gene record 23762
Pubmed identfication 10591208 11278871 11802775
RefSeq identity NM_030758
Classification Pleckstrin homology domain containing Oxysterol binding proteins
Havana BLAST/BLAT OTTHUMG00000151153

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