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p-H2AX Antibody

p-H2AX Antibody size: 0.1ml 354

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 354
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namep-H2AX Primary Polyclonal Antibody
Also known asp-H2AX PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target Antigenp-H2AX
SpecificityThis is a highly specific antibody against p-H2AX
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration5ug/ul
SourceSynthetic peptide
Gene ID number3014
Swiss ProtP16104
Tested ApplicationsWB
Recommended dilutionsWB (1:5000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen DNA accessibility is regulated via a complex set of post-translational modifications of histones, DNA repair, DNA replication and chromosomal stability, Histones thereby play a central role in transcription regulation, Nucleosomes wrap and compact DNA into chromatin, Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation, also called histone code, and nucleosome remodeling, limiting DNA accessibility to the cellular machineries which require DNA as a template, Variant histone H2A which replaces conventional H2A in a subset of nucleosomes
Purification methodAffinity purification
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names H2A, H2A/X, H2AFX, Histone H2A, Histone H2AX, H2AX, X, X
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetp-H2AX
Short namep-H2AX Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namep-H2AX (Antibody to)
Alternative techniqueantibodies
Identity 4739
Gene H2AFX
Long gene name H2A histone family member X
Synonyms gene H2AX
Synonyms gene name H2A histone family, member X
Locus 11q23, 3
Discovery year 1994-11-22
GenBank acession X14850
Entrez gene record 3014
Pubmed identfication 8076949
RefSeq identity NM_002105
Classification Histones
Havana BLAST/BLAT OTTHUMG00000166196

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