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p107(Ser975) Antibody

p107(Ser975) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namep107(Ser975) Primary Polyclonal Antibody
Also known asp107(Ser975) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target Antigenp107 Ser975
SpecificityThis is a highly specific antibody against p107 Ser975
Modification(s)Phosphorylation
Modification site(s)Ser975
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range950-1000/1068
Subcellular locationNucleus
SourceKLH conjugated synthetic phosphopeptide derived from human RBL1 around the phosphorylation site of Ser975
Gene ID number5933
Swiss ProtP28749
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Controls histone H4 'Lys-20' trimethylation, Directly involved in heterochromatin formation by maintaining overall chromatin structure and, Forms a complex with adenovirus E1A and with SV40 large T antigen, May act as a tumor suppressor, May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding, Potent inhibitor of E2F-mediated trans-activation, Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters, Recruits and targets histone methyltransferases KMT5B and KMT5C, in particular, leading to epigenetic transcriptional repression, that of constitutive heterochromatin by stabilizing histone methylation, Key regulator of entry into cell division
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 107 kDa retinoblastoma-associated protein, CP107, RBL1, Retinoblastoma-like protein 1, p107, PRB1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetp107(Ser975)
Short namep107(Ser975) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namep107(Ser975) (Antibody to)
Alternative techniqueantibodies

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