Name : p47-phox Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4964576704
| Long name | p47-phox Primary Polyclonal Antibody |
| Also known as | p47-phox PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | p47-phox |
| Specificity | This is a highly specific antibody against p47-phox |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p47-phox |
| Gene ID number | 653361 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Both p47-phox and p67-phox contain two Src homology 3 (SH3) domains, During activation of the NADPH oxidase, The C-terminal SH3 domain of p67-phox has been shown to interact with the proline-rich domain of p47-phox, The cytosolic proteins p47-phox and p67-phox, also designated neutrophil cytosol factor (NCF)1 and NCF2, are required for activation of the superoxide-producing NADPH oxidase in neutrophils and other phagocytic cells, p47-phox and p67-phox migrate to the plasma membrane where they associate with cytochrome b558 and the small G protein Rac to form the functional enzyme complex, respectively, suggesting that p47-phox may faciliate the transport of p67-phox to the membrane, The heredity chronic granulomatous disease (CGF) has been linked to mutations in p47-phox and p67-phox |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Kip1, cyclin-dependent kinase inhibitor 1B, cyclin-dependent kinase inhibitor 1B p27, Cyclin-dependent kinase inhibitor p27 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | p47-phox |
| Short name | p47-phox Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | p47-phox (Antibody to) |
| Alternative technique | antibodies |