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P53(wt-p53) (D2F7) Monoclonal Antibody

P53(wt-p53) (D2F7) Monoclonal Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameP53(wt-p53) (D2F7) Monoclonal Antibody
Also known asP53(wt-p53) (D2F7) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenP53wt-p53
SpecificityThis is a highly specific antibody against P53wt-p53
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone numberD2F7
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human P53(wt-p53)
Gene ID number7157
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 20937277), Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms, DNA binding, DNA repair, Feb 2013], Mutations in this gene are associated with a variety of human cancers, The encoded protein responds to diverse cellular stresses to regulate expression of target genes, [provided by RefSeq, and oligomerization domains, apoptosis, including hereditary cancers such as Li-Fraumeni syndrome, or changes in metabolism, senescence, thereby inducing cell cycle arrest, This gene encodes a tumor suppressor protein containing transcriptional activation
Purification methodPurified by Protein G
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Antigen NY-CO-13, Cellular tumor antigen p53, Cys 51 Stop, HGNC11998, LFS1, P53_HUMAN, Phosphoprotein p53, TP53, TP53, TRP53, Transformation related protein 53, Tumor protein p53, Tumour Protein p53, Wtp53, p53, p53 Cellular Tumor Antigen, p53 Tumor Suppressor, Widespread p53
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetP53(wt-p53) (D2F7) Monoclonal
Short nameP53(wt-p53) (D2F7) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative nameP53(wt-p53) (D2F7) monoclonal (Antibody to)
Alternative techniqueantibodies
Identity 11998
Gene TP53
Long gene name tumor protein p53
Synonyms p53 LFS1
Synonyms name Li-Fraumeni syndrome
Locus 17p13, 1
Discovery year 1986-01-01
GenBank acession AF307851
Entrez gene record 7157
Pubmed identfication 6396087 3456488 2047879
RefSeq identity NM_000546
Havana BLAST/BLAT OTTHUMG00000162125
Locus Specific Databases IARC TP53 Mutation Database p53 UMD TP53 mutation database Database of Germline p53 Mutations MUTP53LOAD, Mutant p53 Loss Of Activity Database LRG_321

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