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p62 Antibody

p62 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenp62
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity African Green Monkey , Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:50-1:100, Western blot: 1:1000
NotesTitration of the p62 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis p62 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q13501
PurityAntigen affinity
Description Cellular depletion studies of SQSTM1/p62 have indicated a role for association with LC3 and aggregate proteins in order to facilitate normal formation of the autophagosome, SQSTM1/p62 also appears to play a role in macroautophagic removal of intracellular protein aggregates, This protein is involved in cell differentiation, This protein may play a role in titin/TTN downstream signaling in muscle cells, and may also regulate signaling cascades through ubiquitination, apoptosis, immune response and regulation of K(+) channels, nerve growth factor (NGF) and interleukin-1, SQSTM1/p62 is an adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha
ImmunogenA portion of amino acids 317-346 from the human protein was used as the immunogen for this p62 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the p62 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetp62
Short namep62 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namep62 (Antibody to)
Alternative techniqueantibodies
Identity 8066
Gene NUP62
Long gene name nucleoporin 62
Synonyms gene name nucleoporin 62kDa
Synonyms p62 DKFZp547L134 IBSN SNDI MGC841 FLJ20822 FLJ43869
Synonyms name nuclear pore glycoprotein p62
Locus 19q13, 33
Discovery year 2000-01-06
GenBank acession X58521
Entrez gene record 23636
Pubmed identfication 1915414
RefSeq identity NM_153719
Classification Nucleoporins
Havana BLAST/BLAT OTTHUMG00000183077

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