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PA26 Antibody, Biotin Conjugated

PA26 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, PA26 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPA26
SpecificityThis is a highly specific antibody against PA26
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SESN1/PA26
Gene ID number27244
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A related DNA-damage inducible gene, An additional GADD related gene, GADD 34 synergizes with GADD 45 or GADD 153 in suppressing cell growth, GADD 45 stimulates DNA excision repair in vitro and inhibits entry of cells into S phase, PA26, PA26-T2 and PA26-T3, PEG-3 (progression elevated gene-3) shares significant homology with GADD 34 and is inducible by DNA damage, The p53 tumor suppressor is required for one such G1 checkpoint and functions to upregulate expression of GADD 45 and the mitotic inhibitory protein p21, Three isoforms of PA26 have been identified as PA26-T1, and it apparently acts in concert with GADD 153 in inducing growth arrest, is a possible target of p53, presumably to allow time for DNA repair prior to entry into S and M phase, respectively, Cell cycle progression is subject to arrest at G1 and G2 checkpoints in response to DNA damage
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms SEST1 PA26
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPA26 Conjugated
Short name Conjugated, PA26 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, PA26 (Antibody to)
Alternative techniqueantibodies
Identity 21595
Gene SESN1
Long gene name sestrin 1
Locus 6q21
Discovery year 2003-09-03
GenBank acession AF033120
Entrez gene record 27244
Pubmed identfication 9926927 7938006
RefSeq identity NM_014454
Havana BLAST/BLAT OTTHUMG00000015338

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