| Long name | PAK2 Primary Polyclonal Antibody |
| Also known as | PAK2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PAK2 |
| Specificity | This is a highly specific antibody against PAK2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PAK2 |
| Gene ID number | 5062 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | CDC42 and RAC1, PAK2 also interacts with and is activated by HIV1 Nef, The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and have been implicated in a wide range of biological activities, The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 65-KD, CB422, EC 2, Gamma PAK, Kinase, PAK 2, PAK65, PAKgamma, S6 H4 kinase, Serine threonine protein kinase PAK 2, hPAK65, p21 CDKN1A-activated kinase 2a, p21 protein Cdc42 Rac activated kinase 2, p21 protein Cdc42/Rac-activated kinase 2, p21-activated kinase, p21-activated protein kinase I, p21CDKN1A activated kinase 2, p58, p65PAK, 1, 7, 11, p21 activated kinase 2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PAK2 |
| Short name | PAK2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | p21 protein (Cdc42/Rac)-activated kinase 2 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | PAK2 and IDBG-634020 and ENSBTAG00000047856 and 513673, PAK2 and IDBG-71333 and ENSG00000180370 and 5062, PAK65 and PAKgamma, Pak2 and IDBG-153570 and ENSMUSG00000022781 and 224105, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007015 and actin filament organization and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0016032 and viral process and biological process this GO :0016310 and phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0019901: protein kinase binding, this GO :0030296: protein tyrosine kinase activator activity, this GO :0042802: identical protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901: protein kinase binding and also this GO :0030296: protein tyrosine kinase activator activity and also this GO :0042802: identical protein binding, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030296 and protein tyrosine kinase activator activity and molecular function this GO :0031295 and T cell costimulation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0040008 and regulation of growth and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0061098 and positive regulation of protein tyrosine kinase activity and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001271 and negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis and biological process, p21 protein (Cdc42/Rac)-activated kinase 2 |
| Identity | 8591 |
| Gene | PAK2 |
| Long gene name | p21 (RAC1) activated kinase 2 |
| Synonyms gene name | p21 (CDKN1A)-activated kinase 2 p21 protein (Cdc42/Rac)-activated kinase 2 |
| Synonyms | PAK65 PAKgamma |
| Synonyms name | S6/H4 kinase |
| Locus | 3q29 |
| Discovery year | 1998-03-25 |
| GenBank acession | U24153 |
| Entrez gene record | 5062 |
| Pubmed identfication | 7744004 7618083 |
| RefSeq identity | NM_002577 |
| Havana BLAST/BLAT | OTTHUMG00000155534 |
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