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PAK4 Antibody

PAK4 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePAK4 Primary Polyclonal Antibody
Also known asPAK4 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPAK4
SpecificityThis is a highly specific antibody against PAK4
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PAK4
Gene ID number10298
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen All PAK family members are characterized by the presence of p21-binding domain, Current data strongly implicates PAK-4 in oncogenesis, PAK4 is frequently overexpressed in human tumor cell lines of various tissue origins, Phosphospecific directed against serine 474 detect activated PAK4 on the Golgi membrane when PAK4 is co-expressed with activated Cdc42, Serine (Ser-474) is the likely autophosphorylation site in the kinase domain of PAK4 in vivo, and lipids, and transcription, apoptosis, dynamics of the cytoskeleton, including the cell cycle, oncogenic transformation, p21-activated kinases are regulated by the small GTP-binding proteins Rac and Cdc42, which stimulate autophosphorylation and phosphorylation of exogenous substrates, p21-activated kinases (PAKs) belong to the family of serine/threonine kinases involved in the control of various cellular processes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names KIAA1142, PAK 4, PAK4_HUMAN, Protein kinase related to S, Serine threonine kinase PAK 4, Serine/threonine protein kinase PAK 4, Serine/threonine protein kinase PAK4, p21CDKN1A activated kinase 4, cerevisiae STE20 effector for Cdc42Hs, p21 activated kinase 4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPAK4
Short namePAK4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePAK4 (Antibody to)
Alternative techniqueantibodies
Identity 16059
Gene PAK4
Long gene name p21 (RAC1) activated kinase 4
Synonyms gene name p21(CDKN1A)-activated kinase 4 p21 protein (Cdc42/Rac)-activated kinase 4
Locus 19q13, 2
Discovery year 2001-07-12
GenBank acession AJ011855
Entrez gene record 10298
Pubmed identfication 9822598 10461188
Havana BLAST/BLAT OTTHUMG00000182800

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