Name : PARK2(Ser101) Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN7647352449
| Long name | ALEXA FLUOR 555 Conjugated, PARK2(Ser101) Polyclonal Antibody |
| Also known as | Anti-PARK2 Ser101 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PARK2 Ser101 |
| Specificity | This is a highly specific antibody against PARK2 Ser101 |
| Modification | Phosphorylation |
| Modification Site | Ser101 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PARK2 around the phosphorylation site of Ser101 |
| Gene ID Number | 5071 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Autosomal Recessive Juvenile Parkinsonism (AR-JP) is a recently described form of Parkinson's Disease that has been linked to a gene that codes for parkin, Parkin, The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, a 52 kDa protein, has a suggested role in the ubiquitin/proteasome pathway for protein degradation, is characterized by the loss of dopaminergic neurons and the presence of Lewy bodies (comprised of alpha synuclein and parkin inclusions), the second most common neurodegenerative disease after Alzheimer's Disease, thus targeting them for degradation by the proteasome, Parkinson's Disease |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | PDJ AR-JP parkin PRKN |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | PARK2(Ser101) |
| Short name | PARK2(Ser101) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, PARK2(Ser101) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 8607 |
| Gene | PARK2 |
| Long gene name | parkin RBR E3 ubiquitin protein ligase |
| Synonyms gene name | E3 ubiquitin protein ligase (parkin) , Parkinson disease (autosomal recessive, juvenile) 2, parkin parkinson protein 2 |
| Synonyms name | E3 ubiquitin ligase |
| Locus | 6q26 |
| Discovery year | 1997-08-18 |
| Entrez gene record | 5071 |
| Pubmed identfication | 9560156 9570960 |
| Classification | Parkinson disease associated genes RBR E3 ubiquitin ligases |
| Havana BLAST/BLAT | OTTHUMG00000015970 |
| Locus Specific Databases | Parkinson', s disease Mutation Database |