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PER1 Antibody

PER1 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPER1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the PER1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis PER1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O15534
PurityAntigen affinity
Description By fluorescence in situ hybridization, Drosophila, Homolog of, RNA abundance of rigui changed 2, Shigeyoshi et al, Sun et al, Sun et al, They found that Per1 is rapidly induced by short duration exposure to light at levels sufficient to reset the clock, Von Gall et al, also known as PER or RIGUI, designated mouse Per1 by them, expression rose during the light period and fell during the dark period, i, is a protein that in humans is encoded by the PER1 gene, the expression of rigui oscillated over a 24-hour period, which exhibits robust rhythmic expression in the SCN, which occurs through the nocturnal activation of melatonin mt1 receptors, with highest expression at onset of dark in a 12-hour light/dark cycle, (1997) examined the effects of light on rigui, (1997) found that in mouse retina, (1997) mapped the human PER1 gene to 17p12, (2002) demonstrated that cycling expression of the clock gene Per1 in rodent pituitary cells depends on the heterologous sensitization of the adenosine A2B receptor, 9-fold between highest and lowest levels in mouse retina, Period, e
ImmunogenAn amino acid sequence from the N-terminus of human PER-1(RDFTQEKSVFCRIR) was used as the immunogen for this PER1 antibody (100% mouse homology)
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PER1 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPER1
Short namePER1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePER1 (Antibody to)
Alternative techniqueantibodies
Identity 8845
Gene PER1
Long gene name period circadian clock 1
Synonyms gene PER
Synonyms gene name period (Drosophila) homolog 1 period homolog 1 (Drosophila)
Synonyms RIGUI
Locus 17p13, 1
Discovery year 1997-10-21
GenBank acession AB002107
Entrez gene record 5187
Pubmed identfication 9323128
Havana BLAST/BLAT OTTHUMG00000178317

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