Name : PFKL (Ser775) Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN2519310652
| Long name | ALEXA FLUOR 350 Conjugated, PFKL (Ser775) Polyclonal Antibody |
| Also known as | Anti-PFKL Ser775 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PFKL Ser775 |
| Specificity | This is a highly specific antibody against PFKL Ser775 |
| Modification | Phosphorylation |
| Modification Site | Ser775 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PFKL around the phosphorylation site of Ser775 |
| Gene ID Number | 5211 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Mammalian PFK is a tetramer made up of diverse combinations of three isoenzymes: muscle (PFK-1), Overexpression of PFKL in transgenic mice results in a diminished glucose-induced insulin response, PFKL (phosphofructokinase, PFKL is expressed at high levels in Down's syndrome (DS) patients, also referred to as PFK-B (Phosphofructo-1-kinase isozyme B), liver (PFKL) and platelet (PFKP), liver), phosphofructokinase 1 or phosphohexokinase, predominates in organs with active gluconeogenesis, such as liver and kidney, suggesting a possible role for PFKL in the pathogenesis of DS, which suggests that PFKL may play a role in glucose-induced insulin secretion, 6-bisphosphate, Phosphofructokinases (PFKs) are regulatory glycolytic enzymes that catalyze the irreversible conversion of fructose-6-phosphate to fructose-1 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | PFKL (Ser775) |
| Short name | PFKL (Ser775) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, PFKL (Ser775) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 8876 |
| Gene | PFKL |
| Long gene name | liver type , phosphofructokinase |
| Locus | 21q22, 3 |
| Discovery year | 1986-01-01 |
| Entrez gene record | 5211 |
| Havana BLAST/BLAT | OTTHUMG00000086910 |