PHD3 Antibody

PHD3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	PHD3 Primary Polyclonal Antibody
Also known as	PHD3 PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	PHD3
Specificity	This is a highly specific antibody against PHD3
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from PHD3
Gene ID number	112399
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Egln3, Expressed athigher levels in heart (cardiac myocytes, Functions as a cellular oxygen sensor and, HIF-PH3, HIF-prolyl hydroxylase 3, HPH-1, Hydroxylates HIF-1 alpha at 'Pro-564', Hypoxia-inducible factor prolyl hydroxylase 3, May play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue, Nucleus, Prolyl hydroxylase domain-containing protein 3, Promotes cell death through a caspase-dependent mechanism, Widely expressed at low levels, [Catalytic Activity] An HIF alpha chain L-proline + 2-oxoglutarate+ O(2) = An HIF alpha chain trans-4-hydroxy-L-proline + succinate + CO(2), [Subcellular Location] Cytoplasm, and HIF-2 alpha, aortic endothelial cells and coronary artery smooth muscle) and placenta, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex, under normoxic conditions, )Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins, PHD3 (Egl nine homolog 3
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	EGLN3, Factor responsive smooth muscle protein, H Prolyl Hydroxylase 3, HP4H3, HPH3, P4H3, Prolyl Hydroxylase Domain Containing Protein 3, SM20, elegans 3, EGL9 homolog of C
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	PHD3
Short name	PHD3 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	PHD3 (Antibody to)
Alternative technique	antibodies
Identity	14661
Gene	EGLN3
Long gene name	egl-9 family hypoxia inducible factor 3
Synonyms gene name	egl nine homolog 3 (C, elegans)
Synonyms	PHD3 HIFPH3
Synonyms name	HIF prolyl hydroxylase 3
Locus	14q13, 1
Discovery year	2001-08-21
GenBank acession	AJ310545
Entrez gene record	112399
Havana BLAST/BLAT	OTTHUMG00000029498

PHD3 Antibody

PHD3 Antibody size: 0.1ml 263

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