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Phospho-CDC25B Antibody (pS187)

Phospho-CDC25B Antibody (pS187) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPhospho-CDC25B (pS187)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB, IHC
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the phospho-CDC25B antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-CDC25B antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P30305
PurityAntigen affinity
Description CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis, CDC25B has oncogenic properties, CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals, Multiple transcript variants for this gene exist, The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2, although its role in tumor formation has not been determined, CDC25B is a member of the CDC25 family of phosphatases
ImmunogenThis phospho-CDC25B antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS187 of human CDC25B
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-CDC25B antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPhospho-CDC25B (pS187)
Short namePhospho-CDC25B Antibody (pS187)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namephosphorilated-CDC25B (Antibody to) (pS187)
Alternative techniqueantibodies
Identity 1726
Gene CDC25B
Long gene name cell division cycle 25B
Synonyms gene name cell division cycle 25B cell division cycle 25 homolog B (S, cerevisiae) cell division cycle 25 homolog B (S, pombe)
Locus 20p13
Discovery year 1992-07-31
Entrez gene record 994
Pubmed identfication 1836978
RefSeq identity NM_021874
Classification Class III Cys-based CDC25 phosphatases
Havana BLAST/BLAT OTTHUMG00000031764

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