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Phospho-KDR Antibody (pY1175)
Phospho-KDR Antibody (pY1175) size: 0.4 ml 406
Supplier
NJS POLY
Price
406
Size
0.4 ml
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| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Phospho-KDR (pY1175) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, DB |
| Recommended dilutions | Dot blot: 1:500 |
| Notes | Titration of the phospho-KDR antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This phospho-KDR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P35968 |
| Purity | Antigen affinity |
| Description | It functions as the main mediator of VEGF-induced endothelial proliferation, P2Y purine nucleotide receptor, T-cell protein tyrosine phosphatase, The signalling and trafficking of this receptor are regulated by multiple factors, This gene encodes one of the two receptors of the VEGF, This receptor, etc, including Rab GTPase, integrin alphaVbeta3, is a type III receptor tyrosine kinase, known as kinase insert domain receptor, migration, survival, tubular morphogenesis and sprouting, Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells |
| Immunogen | This phospho-KDR antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY1175 of human KDR |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-KDR antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Phospho-KDR (pY1175) |
| Short name | Phospho-KDR Antibody (pY1175) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | phosphorilated-kinase insert domain receptor (a type III receptor tyrosine kinase) (Antibody to) (pY1175) |
| Alternative technique | antibodies |
| Alternative to gene target | CD309 and FLK1 and VEGFR and VEGFR2, KDR and IDBG-19161 and ENSG00000128052 and 3791, KDR and IDBG-642352 and ENSBTAG00000000782 and 407170, Kdr and IDBG-172240 and ENSMUSG00000062960 and 16542, nuclei, this GO :0001525 and angiogenesis and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0001945 and lymph vessel development and biological process this GO :0002042 and cell migration involved in sprouting angiogenesis and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003158 and endothelium development and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0005021 and vascular endothelial growth factor-activated receptor activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016032 and viral process and biological process this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0004716: receptor signaling protein tyrosine kinase activity and also this GO :0005021: vascular endothelial growth factor-activated receptor activity and also this GO :0005178: integrin binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0004716: receptor signaling protein tyrosine kinase activity, this GO :0005021: vascular endothelial growth factor-activated receptor activity, this GO :0005178: integrin binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0019838: growth factor binding, this GO :0038085: vascular endothelial growth factor binding, this GO :0051879: Hsp90 protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019838: growth factor binding and also this GO :0038085: vascular endothelial growth factor binding and also this GO :0051879: Hsp90 protein binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019838 and growth factor binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030054 and cell junction and cellular component this GO :0030097 and hemopoiesis and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030324 and lung development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0035162 and embryonic hemopoiesis and biological process this GO :0035584 and calcium-mediated signaling using intracellular calcium source and biological process this GO :0035924 and cellular response to vascular endothelial growth factor stimulus and biological process this GO :0038083 and peptidyl-tyrosine autophosphorylation and biological process this GO :0038084 and vascular endothelial growth factor signaling pathway and biological process this GO :0038085 and vascular endothelial growth factor binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043129 and surfactant homeostasis and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045121 and membrane raft and cellular component this GO :0045165 and cell fate commitment and biological process this GO :0045446 and endothelial cell differentiation and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048010 and vascular endothelial growth factor receptor signaling pathway and biological process this GO :0048286 and lung alveolus development and biological process this GO :0048469 and cell maturation and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050927 and positive regulation of positive chemotaxis and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0051879 and Hsp90 protein binding and molecular function this GO :0051894 and positive regulation of focal adhesion assembly and biological process this GO :0055074 and calcium ion homeostasis and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071944 and cell periphery and cellular component this GO :0097443 and sorting endosome and cellular component this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process this GO :2001214 and positive regulation of vasculogenesis and biological process, kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Identity | 6307 |
| Gene | KDR |
| Long gene name | kinase insert domain receptor |
| Synonyms gene name | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Synonyms | FLK1 VEGFR VEGFR2 CD309 |
| Synonyms name | vascular endothelial growth factor receptor 2 fetal liver kinase 1 |
| Locus | 4q12 |
| Discovery year | 1991-07-10 |
| GenBank acession | AF035121 |
| Entrez gene record | 3791 |
| Pubmed identfication | 1417831 |
| Classification | I-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000128734 |
| Locus Specific Databases | The Globin Gene Server |