Name : Phospho-PARP1 Antibody (pS864)
Supplier : NJS POLY
Price :406
SKU : GEN7170870374
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Phospho-PARP1 (pS864) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, DB |
| Recommended dilutions | Dot blot: 1:500 |
| Notes | Titration of the phospho-PARP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This phospho-PARP1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P09874 |
| Purity | Antigen affinity |
| Description | In addition, The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, and may participate in the pathophysiology of type I diabetes, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage, poly(ADP-ribosyl)transferase, proliferation, this enzyme may be the site of mutation in Fanconi anemia, which modifies various nuclear proteins by poly(ADP-ribosyl)ation, This gene encodes a chromatin-associated enzyme |
| Immunogen | This phospho-PARP1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS864 of human PARP1 |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-PARP1 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Phospho-PARP1 (pS864) |
| Short name | Phospho-PARP1 Antibody (pS864) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | phosphorilated-PARP1 (Antibody to) (pS864) |
| Alternative technique | antibodies |
| Identity | 270 |
| Gene | PARP1 |
| Long gene name | poly(ADP-ribose) polymerase 1 |
| Synonyms gene | PPOL ADPRT |
| Synonyms gene name | ADP-ribosyltransferase (NAD+, member 1 , poly (ADP-ribose) polymerase) poly (ADP-ribose) polymerase family |
| Synonyms | PARP |
| Locus | 1q42, 12 |
| Discovery year | 1986-01-01 |
| GenBank acession | BC037545 |
| Entrez gene record | 142 |
| Pubmed identfication | 10964595 |
| RefSeq identity | NM_001618 |
| Classification | Zinc fingers PARP-type Zinc fingers Poly(ADP-ribose) polymerases |
| Havana BLAST/BLAT | OTTHUMG00000037556 |