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Phospho-SHP2 Antibody (pY584)

Phospho-SHP2 Antibody (pY584) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPhospho-SHP2 (pY584)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB, DB
Recommended dilutionsDot blot: 1:500, Western blot: 1:2000
NotesTitration of the phospho-SHP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-SHP2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q06124
PurityAntigen affinity
Description PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, This PTP contains two tandem Src homology-2 domains, This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, and cell migration, and oncogenic transformation, differentiation, metabolic control, mitotic cycle, such as mitogenic activation, transcription regulation, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates, SHP2 is a member of the protein tyrosine phosphatase (PTP) family
ImmunogenThis phospho-SHP2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY584 of human SHP2
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-SHP2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPhospho-SHP2 (pY584)
Short namePhospho-SHP2 Antibody (pY584)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namephosphorilated-SHP2 (Antibody to) (pY584)
Alternative techniqueantibodies
Identity 9644
Gene PTPN11
Long gene name non-receptor type 11 , protein tyrosine phosphatase
Synonyms gene NS1
Synonyms gene name Noonan syndrome 1
Synonyms BPTP3 SH-PTP2 SHP-2 PTP2C SHP2
Locus 12q24, 13
Discovery year 1993-03-03
GenBank acession D13540
Entrez gene record 5781
Pubmed identfication 7894486 1280823
Classification Protein tyrosine phosphatases, non-receptor type SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000134334
Locus Specific Databases LRG_614

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