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PITX2 Antibody

PITX2 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPITX2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the PITX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis PITX2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q99697
PurityAntigen affinity
Description A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development, Alternatively spliced transcript variants encoding distinct isoforms have been described, Mutations in this gene are associated with Axenfeld-Rieger syndrome, The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression, This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin, and sporadic cases of Peters anomaly, iridogoniodysgenesis syndrome, is involved in the development of the eye, tooth and abdominal organs, which is in the bicoid class of homeodomain proteins, This gene encodes a member of the RIEG/PITX homeobox family
ImmunogenA portion of amino acids 42-71 from the human protein was used as the immunogen for this PITX2 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PITX2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPITX2
Short namePITX2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePITX2 (Antibody to)
Alternative techniqueantibodies
Identity 9005
Gene PITX2
Long gene name paired like homeodomain 2
Synonyms gene IRID2 IHG2 RIEG RIEG1 RGS
Synonyms gene name paired-like homeodomain transcription factor 2 paired-like homeodomain 2
Synonyms IGDS RS Brx1 Otlx2 ARP1
Locus 4q25
Discovery year 1992-10-05
GenBank acession U69961
Entrez gene record 5308
Pubmed identfication 9539779 7581385
Classification PRD class homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000132837

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