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PKC alpha Antibody

PKC alpha Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPKC alpha
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IF, WB, IHC
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the PKC alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis PKC alpha antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P17252
PurityPurified
Description Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells, Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes, PKC alpha is one of the PKC family members, PKC family members also serve as major receptors for phorbol esters, PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways, This kinase has been reported to play roles in many different cellular processes, a class of tumor promoters, and cell volume control, cell cycle checkpoint, cell transformation, such as cell adhesion, Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol
ImmunogenA portion of amino acids 299-329 from the human protein was used as the immunogen for this PKC alpha antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PKC alpha antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPKC alpha
Short namePKC alpha Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePKC a (Antibody to)
Alternative techniqueantibodies
Identity 30500
Gene PRRT2
Long gene name proline rich transmembrane protein 2
Synonyms gene ICCA DYT10
Synonyms gene name infantile convulsions and paroxysmal choreoathetosis dystonia 10 proline-rich transmembrane protein 2
Synonyms FLJ25513 DKFZp547J199 IFITMD1 FICCA DSPB3 PKC EKD1
Synonyms name interferon induced transmembrane protein domain containing 1
Locus 16p11, 2
Discovery year 2005-11-25
GenBank acession BC011405
Entrez gene record 112476
Pubmed identfication 22101681 22243967
RefSeq identity NM_145239
Classification Proline rich transmembrane proteins
Havana BLAST/BLAT OTTHUMG00000177142

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