Name : PKC alpha Antibody
Supplier : NJS POLY
Price :199
SKU : GEN1896185920
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | PKC alpha |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IF, WB, IHC |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the PKC alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This PKC alpha antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P17252 |
| Purity | Purified |
| Description | Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells, Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes, PKC alpha is one of the PKC family members, PKC family members also serve as major receptors for phorbol esters, PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways, This kinase has been reported to play roles in many different cellular processes, a class of tumor promoters, and cell volume control, cell cycle checkpoint, cell transformation, such as cell adhesion, Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol |
| Immunogen | A portion of amino acids 299-329 from the human protein was used as the immunogen for this PKC alpha antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PKC alpha antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | PKC alpha |
| Short name | PKC alpha Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | PKC a (Antibody to) |
| Alternative technique | antibodies |
| Identity | 30500 |
| Gene | PRRT2 |
| Long gene name | proline rich transmembrane protein 2 |
| Synonyms gene | ICCA DYT10 |
| Synonyms gene name | infantile convulsions and paroxysmal choreoathetosis dystonia 10 proline-rich transmembrane protein 2 |
| Synonyms | FLJ25513 DKFZp547J199 IFITMD1 FICCA DSPB3 PKC EKD1 |
| Synonyms name | interferon induced transmembrane protein domain containing 1 |
| Locus | 16p11, 2 |
| Discovery year | 2005-11-25 |
| GenBank acession | BC011405 |
| Entrez gene record | 112476 |
| Pubmed identfication | 22101681 22243967 |
| RefSeq identity | NM_145239 |
| Classification | Proline rich transmembrane proteins |
| Havana BLAST/BLAT | OTTHUMG00000177142 |