| Alternative name1 | APO3, Apo-3, Apoptosis-inducing Receptor AIR, Apoptosis-mediating Receptor DR3, Apoptosis-mediating Receptor TRAMP, DDR3, DR3, DSMA4, Death Domain Receptor 3, Guanine N, Anti-PLEKHG5 (Pleckstrin Homology Domain Containing Family G (with RhoGef domain) Member 5 |
| Alternative name2 | APO3, Apo-3, Apoptosis-inducing Receptor AIR, Apoptosis-mediating Receptor DR3, Apoptosis-mediating Receptor TRAMP, DDR3, DR3, DSMA4, Death Domain Receptor 3, Guanine N, PLEKHG5 (Pleckstrin Homology Domain Containing Family G (with RhoGef domain) Member 5 |
| Alternative name3 | APO3, Apo-3, Apoptosis-inducing Receptor AIR, Apoptosis-mediating Receptor DR3, Apoptosis-mediating Receptor TRAMP, DDR3, DR3, DSMA4, Death Domain Receptor 3, Guanine N, PLEKHG5 (Pleckstrin Homology Domain Containing Family G (with RhoGef domain) Member 5 |
| Alternative name4 | PLEKHG5 |
| Alternative name5 | APO3, Apo-3, Apoptosis-inducing Receptor AIR, Apoptosis-mediating Receptor DR3, Apoptosis-mediating Receptor TRAMP, DDR3, DR3, DSMA4, Death Domain Receptor 3, Guanine N, Anti -PLEKHG5 (Pleckstrin Homology Domain Containing Family G (with RhoGef domain) Member 5 |
| Other names | Guanine nucleotide exchange factor 720, NFkB activating protein, OTTHUMP00000001050, OTTHUMP00000001051, OTTHUMP00000001052, OTTHUMP00000001053, OTTHUMP00000001054, OTTHUMP00000001055, PH domain-containing family G member 5, Pleckstrin homology domain-containing family G member 5, family G (with RhoGef domain) member 5, guanine nucleotide exchange factor 720, novel PH domain-containing protein, pleckstrin homology domain containing, pleckstrin homology domain containing family G member 5, pleckstrin homology domain-containing family G member 5, pleckstrin homology domain-containing family G member 5 isoform a |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | DSMA4, GEF720, KIAA0720, KIAA0720, PLEKHG5, RP4-650H14, 3, PLEKHG5 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | N/A |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | Reacts specifically with 98-105kD of human PLEKHG5 |
| Purification method | Serum |
| Form/Appearance | N/A |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Immunohistochemistry (IHC), Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | APO3, Apo-3, DDR3, DR3, DSMA4, Death Domain Receptor 3, Guanine N, Receptor AIR, mediating Receptor DR3, mediating Receptor TRAMP, PLEKHG5 (Pleckstrin Homology Domain Family G (with RhoGef domain) Member 5 |
| Short name | APO3, Apo-3, Apoptosis- Receptor AIR, Apoptosis-mediating Receptor DR3, Apoptosis-mediating Receptor TRAMP, DDR3, DR3, DSMA4, Death Domain Receptor 3, Guanine N Antibody, PLEKHG5 (Pleckstrin Homology Domain Family G (with RhoGef domain) Member 5 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | APO3, Apo-3, DDR3, DR3, DSMA4, Death Domain Receptor 3, Guanine N (Antibody to), family G (including RhoGef domain) member 5 (Pleckstrin Homology Domain Containing family G (including RhoGef domain) Member 5, programmed cellular destruction-inducing Receptor AIR, programmed cellular destruction-mediating Receptor DR3, programmed cellular destruction-mediating Receptor TRAMP, pleckstrin homology domain containing |
| Alternative technique | antibodies |
| Alternative to gene target | Cell surfaces, PLEKHG5 and IDBG-633823 and ENSBTAG00000016728 and 615910, PLEKHG5 and IDBG-87695 and ENSG00000171680 and 57449, Plekhg5 and IDBG-206297 and ENSMUSG00000039713 and 269608, family G (with RhoGef domain) member 5, protein binding, this GO :0004871 and signal transducer activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030139 and endocytic vesicle and cellular component this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0035767 and endothelial cell chemotaxis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043542 and endothelial cell migration and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0005089: Rho guanyl-nucleotide exchange factor activity and also this GO :0005515: protein binding, this GO :0005089: Rho guanyl-nucleotide exchange factor activity, this GO :0005515: protein binding, pleckstrin homology domain containing |
| Identity | 29105 |
| Gene | PLEKHG5 |
| Long gene name | pleckstrin homology and RhoGEF domain containing G5 |
| Synonyms gene name | family G (with RhoGef domain) member 5 , pleckstrin homology domain containing |
| Synonyms | KIAA0720 Syx GEF720 Tech |
| Synonyms name | synectin-binding guanine exchange factor |
| Locus | 1p36, 31 |
| Discovery year | 2005-05-23 |
| GenBank acession | AK024676 |
| Entrez gene record | 57449 |
| Pubmed identfication | 17564964 |
| RefSeq identity | NM_020631 |
| Classification | Pleckstrin homology domain containing |
| Havana BLAST/BLAT | OTTHUMG00000000905 |
| Locus Specific Databases | LRG_262 |
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