Name : POR Antibody / CYPOR / Cytochrome P450 Oxidoreductase
Supplier : NJS POLY
Price :406
SKU : GEN6358524992
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | POR / CYPOR / Cytochrome P450 Oxidoreductase |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Optimal dilution of the POR antibody should be determined by the researcher |
| Intented use | This POR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P16435 |
| Purity | Antigen affinity |
| Description | FAD and FMN, Mutations in this gene have been associated with various diseases, The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain, The protein binds two cofactors, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome, including apparent combined p450C17 and p450C21 deficiency, which allow it to donate electrons directly from NADPH to all microsomal p450 enzymes, POR is a membrane-bound enzyme required for electron transfer from NADPH to Cytochrome p450 in the endoplasmic reticulum of theeukaryotic cell |
| Immunogen | Amino acids RNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTK of human Cytochrome P450 Oxidoreductase were used as the immunogen for the POR antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the POR antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | membrane, Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | POR / CYPOR / Cytochrome P450 Oxidoreductase |
| Short name | POR Antibody / CYPOR / Cytochrome P450 Oxidoreductase |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | POR (Antibody to) / CYPOR / Cytochrome P450 Oxidoreductase |
| Alternative technique | antibodies |
| Identity | 3829 |
| Gene | FRA10A |
| Long gene name | folic acid type, fra(10)(q23, fragile site, rare, 2) , 3) or fra(10)(q24 |
| Locus | 10q23, 2 , 3 or 10q24 |
| Discovery year | 1986-01-01 |
| Pubmed identfication | 15203205 |