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PPM1A(Ser375) Antibody

PPM1A(Ser375) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePPM1A(Ser375) Primary Polyclonal Antibody
Also known asPPM1A(Ser375) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPPM1A Ser375
SpecificityThis is a highly specific antibody against PPM1A Ser375
Modification(s)Phosphorylation
Modification site(s)Ser375
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PPM1A around the phosphorylation site of Ser375
Gene ID number5494
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses, Jul 2008], MAP kinases and MAP kinase kinases, Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, PP2C family members are known to be negative regulators of cell stress response pathways, This phosphatase can also dephosphorylate cyclin-dependent kinases, This phosphatase dephosphorylates, Three alternatively spliced transcript variants encoding distinct isoforms have been described, [provided by RefSeq, and negatively regulates the activities of, and thus may be involved in cell cycle control, which leads to G2/M cell cycle arrest and apoptosis, The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names IA antibody, Mpp alpha, PP2C alpha, PP2C-alpha, PP2CA, PPM 1A, PPM1A, PPM1A_HUMAN, PPPM1A, Protein phosphatase 1A, Protein phosphatase 1A formerly 2C magnesium dependent alpha isoform, Protein phosphatase 1A magnesium dependent alpha, Protein phosphatase 2C alpha, Protein phosphatase 2C alpha isoform, Protein phosphatase 2C isoform alpha, Protein phosphatase 2C isoform alpha, Protein phosphatase IA, PPM1Aphospho S375
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPPM1A(Ser375)
Short namePPM1A(Ser375) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePPM1A(Ser375) (Antibody to)
Alternative techniqueantibodies
Identity 9275
Gene PPM1A
Long gene name Mg2+/Mn2+ dependent 1A , protein phosphatase
Synonyms gene name 1A , Mg2+/Mn2+ dependent, alpha isoform protein phosphatase, magnesium-dependent, protein phosphatase 1A (formerly 2C)
Synonyms MGC9201 PP2Calpha PP2CA
Synonyms name alpha isoform , phosphatase 2C alpha protein phosphatase 2C
Locus 14q23, 1
Discovery year 1993-02-05
GenBank acession S87759
Entrez gene record 5494
Pubmed identfication 1311954
RefSeq identity NM_021003
Classification Mg2+/Mn2+ dependent , Protein phosphatases
Havana BLAST/BLAT OTTHUMG00000140333

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