Filters

PPP4C Antibody, Biotin Conjugated

PPP4C Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, PPP4C Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPPP4C
SpecificityThis is a highly specific antibody against PPP4C
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range260-307/307
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human PP4C
Gene ID number5531
Swiss ProtP60510
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background DNA damage checkpoint signaling, DNA repair, Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity), In response to DNA damage, NF-kappa-B activation and cell migration, The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3, The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-14 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair, activation of c-Jun N-terminal kinase MAPK8, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin, apoptosis, catalyzes RPA2 dephosphorylation, maturation of spliceosomal snRNPs, regulation of histone acetylation, tumor necrosis factor (TNF)-alpha signaling, Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms PP4 PPX
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPPP4C Conjugated
Short name Conjugated, PPP4C Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, PPP4C (Antibody to)
Alternative techniqueantibodies
Identity 9319
Gene PPP4C
Long gene name protein phosphatase 4 catalytic subunit
Synonyms gene name catalytic subunit , catalytic subunit protein phosphatase 4, protein phosphatase 4 (formerly X)
Synonyms name catalytic subunit , protein phosphatase X
Locus 16p11, 2
Discovery year 1993-01-22
Entrez gene record 5531
Pubmed identfication 9177794
RefSeq identity NM_002720
Classification Protein phosphatase catalytic subunits
Havana BLAST/BLAT OTTHUMG00000132113

Similar products

Subscribe to our Newsletter