Name : PRDM1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3968542475
| Long name | PRDM1 Primary Polyclonal Antibody |
| Also known as | PRDM1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PRDM1 |
| Specificity | This is a highly specific antibody against PRDM1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRDM1/Blimp1 |
| Gene ID number | 144423 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Alone, Blimp-1 is a transcriptional repressor that localizes to the nucleus and is considered a master regulator of terminal B-cell development, Blimp-1 is expressed during the late stages of B-cell differentiation in immunoglobulin-secreting plasma cells, Blimp-1 is sufficient to trigger terminal B-cell differentiation, Blimp-1 upregulates the expression of syndecan-1 and J chain, The expression of Blimp-1 defines a checkpoint beyond which fully activated B cells proceed to the plasma cell stage, also designated PRDI-BF1), are induced by Blimp-1 (B lymphocyte-induced maturation protein, as well as in long-lived, bone marrow plasma cells, represses IFN-b gene transcription and associates with HDAC to recruit it to DNA, thereby repressing c-myc, whereas immature and partially activated cells are eliminated, which are terminally differentiated B-cells, The development and differentiation of plasma cells |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | B Lymphocyte Induced Maturation Protein 1, BLIMP-1, BLIMP1, Beta interferon gene positive regulatory domain I binding factor, Beta-interferon gene positive regulatory domain I-binding factor, Blimp-1, PR Domain Containing 1, PR domain containing 1 with ZNF domain, PR domain containing 1 with ZNF domain isoform 2, PR domain containing protein 1, PR domain zinc finger protein 1, PR domain-containing protein 1, PRDI BF1, PRDI binding factor 1, PRDI-BF1, PRDI-binding factor 1, PRDM 1, PRDM1_HUMAN, Positive Regulatory Domain I Binding Factor 1, Positive regulatory domain I-binding factor 1, Prdm1, Blimp 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PRDM1 |
| Short name | PRDM1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | PRDM1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9346 |
| Gene | PRDM1 |
| Long gene name | PR/SET domain 1 |
| Synonyms gene | BLIMP1 |
| Synonyms gene name | PR domain containing 1, with ZNF domain PR domain 1 |
| Synonyms | PRDI-BF1 |
| Locus | 6q21 |
| Discovery year | 1994-09-14 |
| Entrez gene record | 639 |
| Pubmed identfication | 1851123 |
| Classification | Zinc fingers C2H2-type PR/SET domain family |
| Havana BLAST/BLAT | OTTHUMG00000015299 |