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PRDM1 Antibody

PRDM1 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long namePRDM1 Primary Polyclonal Antibody
Also known asPRDM1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPRDM1
SpecificityThis is a highly specific antibody against PRDM1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRDM1/Blimp1
Gene ID number144423
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Alone, Blimp-1 is a transcriptional repressor that localizes to the nucleus and is considered a master regulator of terminal B-cell development, Blimp-1 is expressed during the late stages of B-cell differentiation in immunoglobulin-secreting plasma cells, Blimp-1 is sufficient to trigger terminal B-cell differentiation, Blimp-1 upregulates the expression of syndecan-1 and J chain, The expression of Blimp-1 defines a checkpoint beyond which fully activated B cells proceed to the plasma cell stage, also designated PRDI-BF1), are induced by Blimp-1 (B lymphocyte-induced maturation protein, as well as in long-lived, bone marrow plasma cells, represses IFN-b gene transcription and associates with HDAC to recruit it to DNA, thereby repressing c-myc, whereas immature and partially activated cells are eliminated, which are terminally differentiated B-cells, The development and differentiation of plasma cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names B Lymphocyte Induced Maturation Protein 1, BLIMP-1, BLIMP1, Beta interferon gene positive regulatory domain I binding factor, Beta-interferon gene positive regulatory domain I-binding factor, Blimp-1, PR Domain Containing 1, PR domain containing 1 with ZNF domain, PR domain containing 1 with ZNF domain isoform 2, PR domain containing protein 1, PR domain zinc finger protein 1, PR domain-containing protein 1, PRDI BF1, PRDI binding factor 1, PRDI-BF1, PRDI-binding factor 1, PRDM 1, PRDM1_HUMAN, Positive Regulatory Domain I Binding Factor 1, Positive regulatory domain I-binding factor 1, Prdm1, Blimp 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPRDM1
Short namePRDM1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePRDM1 (Antibody to)
Alternative techniqueantibodies
Identity 9346
Gene PRDM1
Long gene name PR/SET domain 1
Synonyms gene BLIMP1
Synonyms gene name PR domain containing 1, with ZNF domain PR domain 1
Synonyms PRDI-BF1
Locus 6q21
Discovery year 1994-09-14
Entrez gene record 639
Pubmed identfication 1851123
Classification Zinc fingers C2H2-type PR/SET domain family
Havana BLAST/BLAT OTTHUMG00000015299

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